FIBROMYALGIA--CENTRAL FACTORS IN ITS ETIOPATHOGENESIS

本研究的目的是为了更好地了解 纤维肌痛我们目前的主题组包括25纤维肌痛（FM） 10例伴有外伤性症状的FM患者 发病，25名社区居民与FM谁没有寻求治疗， 他们的疼痛症状（非患者）和13名健康对照。 所有 受试者接受疼痛阈值和感觉测试，单光子 脑局部发射型计算机断层显像（SPECT） 静息状态下的血流量（rCBF）和腰椎穿刺， 收集脑脊液进行P物质放射免疫测定， 继续招募受试者，直到我们有25名FM患者， 创伤性发作，50例非FM患者和50例对照。

The purpose of this study is to better understand the etiopathogenesis of fibromyalgia. Our current subject groups consist of 25 fibromyalgia (FM) patients with gradual symptom onset, 10 FM patients with traumatic symptom onset, 25 community residents with FM who have not sought treatment for their painful symptoms (nonpatients), and 13 healthy controls. All subjects undergo pain threshold and sensory testing, single photon emission computed tomographic (SPECT) imaging of brain regional cerebral blood flow (rCBF) during resting conditions, and lumbar puncture to collect cerebrospinal fluid for radioimmunoassay of substance P. We plan to continue subject recruitment until we have 25 FM patients with traumatic onset, 50 nonpatients with FM, and 50 controls.