CLINICAL EXPERIENCE AND USE OF VIGABATRIN IN PATIENTS WITH INFANTILE SPASMS

婴儿痉挛是发生在婴儿身上的一种严重癫痫发作。 婴儿痉挛症患儿的前景很差：大多数 发展残疾，大多数人继续患有严重的癫痫。 ACTH是婴儿痉挛症最常用的治疗方法， 成功至少暂时在约70%，然而，不利影响是 显著 传统的抗惊厥药只是偶尔 有效 氨己烯酸，一种新的抗惊厥药物正在进行安全性评估 和治疗婴儿痉挛症的有效性。

Infantile spasms are a severe type of seizures which occur in infants. The outlook for a child with infantile spasms is poor: most are developmentally disabled, and a majority continue to have severe epilepsy. ACTH is the most commonly used treatment for infantile spasms and is successful at least temporarily in about 70% However, adverse effects are significant. Conventional anticonvulsants are only occassionally effective. Vigabatrin, a new anticonvulsant is being evaluated for safety and efficacy in treating infantile spasms.