ACUTE OTITIS MEDIA--ADJUVANT THERAPY TO IMPROVE OUTCOME
ACUTE OTITIS MEDIA--ADJUVANT THERAPY TO IMPROVE OUTCOME
批准号:
6276403
负责人:
Tasnee Chonmaitree
金额:
$2.69万
依托单位国家:
美国
项目类别:
财政年份:
1997
资助国家:
美国
项目状态:
已结题
起止时间:
1997-12-01 至 1998-11-30
关键词:
antibiotics antihistamines antiinflammatory agents bacterial disease child (0-11) clinical research combination chemotherapy corticosteroids ear disorder chemotherapy exudate /transudate histamine human subject human therapy evaluation leukotrienes longitudinal human study otitis media pediatric pharmacology pediatrics relapse /recurrence virus diseases
中文摘要
尽管有有效的抗生素用于治疗急性胰腺炎
中耳炎(AOM)、治疗失败、持续渗出和
反复发作是很常见的。我们之前已经表明,增加的水平
中间有组胺和白三烯等炎性介质
耳液(MEF)与AOM的不良临床结局有关。在……里面
在这项研究中,我们将测试辅助治疗是否旨在对抗
组胺作用(抗组胺),和/或抑制形成
白三烯和其他致炎物质(皮质类固醇)。
英文摘要
Despite the availability for effective antibiotics for treatment of acute
otitis media (AOM), treatment failures, persistent effusions and
recurrences are common. We have previously shown that increased levels of
inflammatory mediators such as histamine and leukotrienes in the middle
ear fluids (MEFs) are associated with adverse clinical outcome of AOM. In
this study, we will test whether adjuvant therapy aimed at counteracting
histamine actions (antihistamine), and/or inhibiting formation of
leukotrienes and other inflammtory substances (corticosteroid).
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
Respiratory Tract Microbiota and Acute Otitis Media Development in Young Infants
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批准号:8618410
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项目类别:
-
资助金额:$15.44万
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财政年份:2013
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负责人:Tasnee Chonmaitree
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依托单位:
Respiratory Tract Microbiota and Acute Otitis Media Development in Young Infants
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批准号:8766556
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项目类别:
-
资助金额:$15.44万
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财政年份:2013
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负责人:Tasnee Chonmaitree
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依托单位:
PATHOGENESIS OF VIRUS-INDUCED ACUTE OTITIS MEDIA: GENETIC AND ENVIRONMENTAL
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批准号:7952168
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项目类别:
-
资助金额:$0.21万
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财政年份:2009
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负责人:Tasnee Chonmaitree
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依托单位:
LONGITUDINAL STUDY OF ACUTE OTITIS MEDIA (AOM) DEVELOPMENT IN CHILDREN WITH
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批准号:7605386
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项目类别:
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资助金额:$5.09万
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财政年份:2007
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负责人:Tasnee Chonmaitree
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依托单位:
LONGITUDINAL STUDY OF ACUTE OTITIS MEDIA (AOM) DEVELOPMENT IN CHILDREN WITH
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批准号:7378712
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项目类别:
-
资助金额:$18.54万
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财政年份:2006
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负责人:Tasnee Chonmaitree
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依托单位:
CYTOKINE GENE POLYMORPHISM AND SUSCEPTIBILITY TO OTITIS MEDIA
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批准号:7202555
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项目类别:
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资助金额:$1.9万
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财政年份:2005
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负责人:Tasnee Chonmaitree
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依托单位:
LONGITUDINAL STUDY OF ACUTE OTITIS MEDIA (AOM) DEVELOPMENT IN CHILDREN WITH
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批准号:7202568
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项目类别:
-
资助金额:$20.61万
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财政年份:2005
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负责人:Tasnee Chonmaitree
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依托单位:
Pathogenesis of Virus-Induced Acute Otitis Media
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批准号:6937668
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项目类别:
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资助金额:$50.0万
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财政年份:2002
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负责人:Tasnee Chonmaitree
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依托单位:
Pathogenesis of Virus-Induced Acute Otitis Media
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批准号:7114876
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项目类别:
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资助金额:$36.37万
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财政年份:2002
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负责人:Tasnee Chonmaitree
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依托单位:
Pathogenesis of Virus-Induced Acute Otitis Media
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批准号:6793202
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项目类别:
-
资助金额:$49.66万
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财政年份:2002
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负责人:Tasnee Chonmaitree
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依托单位:
Pathogenesis of virus-induced acute otitis media
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批准号:8077371
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项目类别:
-
资助金额:$59.29万
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财政年份:2002
-
负责人:Tasnee Chonmaitree
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依托单位:
Pathogenesis of virus-induced acute otitis media
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批准号:8093169
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项目类别:
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资助金额:$8.57万
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财政年份:2002
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负责人:Tasnee Chonmaitree
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依托单位:
Pathogenesis of Virus-Induced Acute Otitis Media
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批准号:6794864
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项目类别:
-
资助金额:$12.14万
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财政年份:2002
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负责人:Tasnee Chonmaitree
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依托单位:
Pathogenesis of virus-induced acute otitis media
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批准号:8274827
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项目类别:
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资助金额:$45.51万
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财政年份:2002
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负责人:Tasnee Chonmaitree
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依托单位:
Pathogenesis of virus-induced acute otitis media
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批准号:8465053
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项目类别:
-
资助金额:$4.0万
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财政年份:2002
-
负责人:Tasnee Chonmaitree
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依托单位:
Pathogenesis of Virus-Induced Acute Otitis Media
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批准号:6576791
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项目类别:
-
资助金额:$37.25万
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财政年份:2002
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负责人:Tasnee Chonmaitree
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依托单位:
Pathogenesis of virus-induced acute otitis media
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批准号:7646166
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项目类别:
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资助金额:$52.11万
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财政年份:2002
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负责人:Tasnee Chonmaitree
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依托单位:
Pathogenesis of virus-induced acute otitis media
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批准号:8490333
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项目类别:
-
资助金额:$71.71万
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财政年份:2002
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负责人:Tasnee Chonmaitree
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依托单位:
Cytokine gene polymorphism and susceptibility to otitis media
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批准号:6981018
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项目类别:
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资助金额:$2.89万
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财政年份:2002
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负责人:Tasnee Chonmaitree
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依托单位:
Pathogenesis of virus-induced acute otitis media
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批准号:7874663
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项目类别:
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资助金额:$53.44万
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财政年份:2002
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负责人:Tasnee Chonmaitree
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依托单位:
海外基金