NUCLEAR FAMILY COLLECTION FOR THE STUDY OF THE GENETICS OF ASTHMA

这项调查的总体目标是进行遗传学研究。 哮喘的症状。我们将研究100个患有哮喘的核心家庭， 包括所有民族的男子、妇女和5岁及以上的儿童 背景。所有家庭成员都将使用 问卷、过敏性皮肤测试、肺功能研究和血液 血清IgE水平和基因组DNA的研究。有了这个信息，我们 将鉴定和鉴定基因(S)及其产物 参与了哮喘的产生。这一信息将进一步推动我们的 对哮喘的认识，为哮喘的诊断和治疗提供新的方法 治疗。

The overall objective of this investigation is to perform genetic studies of asthma. We will study 100 nuclear families whose members have asthma, including men, women and children 5 years and older of all ethnic backgrounds. All members of the families will be characterized using questionnaires, allergy skin testing, lung function studies, and blood studies for serum IgE levels, and genomic DNA. With this information we will identify and characterize the gene(s) and their products which are involved in the production of asthma. This information will further our understanding of asthma and provide new methods for its diagnosis and treatment.