Gordon Research Conf--Nitric Oxide in Biochem & Biology

“生物化学和生物学中的一氧化氮”戈登研究会议旨在为化学家、生物学家、生物化学家、细胞生物学家、临床医生和其他生物医学科学家提供有关化学和生物系统中一氧化氮和活性氮物种的最新知识。本次研究会议每两年举行一次；下一次会议将于2001年2月4日至8日在加利福尼亚州文图拉的Four Points喜来登港口酒店举行。自1995年以来，已经举行了三次会议，根据大量申请者和会后评价，这些会议被证明是非常有成效的。特别要求提供资金，以支持年轻研究人员担任会议主席和发言者，并部分支持富有成效的博士后和研究生出席会议。本方案所列发言者是根据历届会议主席、联席主席和与会者的建议选出的。几乎所有的演讲者都接受了邀请，展示了他们对一氧化氮生物学和化学的最新研究。讨论的主题包括：活性氮在神经变性、血管疾病和伤口愈合中的作用，选择性抑制一氧化氮合酶同工酶的新策略，一氧化氮与血红蛋白和其他血红素蛋白的反应，以及酪氨酸硝化的生物效应。此外，1998年诺贝尔医学奖得主路易斯·伊格纳罗教授将发表题为《N-羟基精氨酸在一氧化氮合成过程中的生理作用》的全体讲座。预计将举行两次为期两天的海报发布活动，预计将发布50-70张海报。根据戈登会议的规定，总出席人数限制为135人。戈登研究会议为参与者和研究领域的多样性提供了一个极好和必要的论坛。本次戈登研究会议的主要优势是为不同学科的科学家提供了以延长和不间断的方式进行互动的机会。这种类型的互动通常会导致新的合作研究倡议。戈登研究会议聚焦于一氧化氮的生物化学，在探索这一重要和临床相关领域的前沿研究方面发挥了至关重要的作用。

The Gordon Research Conference on "Nitric Oxide in Biochemistry and Biology" is designed to provide chemists, biologists, biochemists, cell biologists, clinicians, and other biomedical scientists with state of the art knowledge on nitric oxide and reactive nitrogen species in chemical and biological systems. This research conference is held every two years; the next meeting will be held February 4-8, 2001, at the Four Points Sheraton Harbortown Hotel, Ventura, California. Three conferences have been held since 1995 and they have proven to be extremely productive based on the large number of applicants and the post-meeting evaluations. Funding is specifically requested to support young investigators as session chairman and speakers as well as to partially support productive post docs and graduate students to attend the meeting. The speakers listed in this program were selected based on suggestions from previous chairs, co-chairs and attendees at the past conferences. Virtually all speakers have accepted the invitation to present their latest research on the biology and chemistry of nitric oxide. Topics to be covered include the roles of reactive nitrogen species in neurodegeneration, vascular disease and wound healing, novel strategies for the selective inhibition of nitric oxide synthase isozymes, reactions of NO with hemoglobin and other heme proteins and the biological effects of tyrosine nitration. In addition, Professor Louis Ignarro, the recipient of the 1998 Nobel Prize in Medicine, will present a Plenary Lecture entitled "The physiological role for N-hydroxyarginine during the synthesis of nitric oxide." Two separate poster sessions of two days each are scheduled for an anticipated 50-70 posters. Total attendance is limited to 135 by Gordon Conference rules. The Gordon Research Conference provides an excellent and needed forum for the diversity of both participants and research areas. The main strength of this Gordon Research Conference is the opportunity offered for scientists in different disciplines to interact in an extended and uninterrupted fashion. This type of interaction generally results in new collaborative research initiatives. The Gordon Research Conference focused on the biological chemistry of nitric oxide plays a crucial role in exploring frontier research in this important and clinically relevant field.