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SPONTANEOUS AIRWAY PRESSURE RELEASE VENTILATION (S-APRV): A NEW CONCEPT

SPONTANEOUS AIRWAY PRESSURE RELEASE VENTILATION (S-APRV): A NEW CONCEPT
自主气道压力释放通气 (S-APRV):一个新概念
批准号:
6290400
负责人:
THEODOR KOLOBOW
金额:
$0.0万
依托单位国家:
美国
项目类别:
财政年份:
--
资助国家:
美国
项目状态:
未结题
起止时间:
至

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中文摘要
翻译
我们在实验动物研究实验室的设置中探索了新的方法和技术,可以改善患者的发病率和死亡率。我们现在已经在绵羊身上证明,在插管和机械通风的情况下,可以通过一种名为气管内肺通气(ITPV)的新方法来消除周期性的气管吸入以清除分泌物,在这种方法中,粘液通过呼气气流持续吸入,而不需要吸入。这项技术有望极大地改善气管马桶,并提高患者的舒适度。我们还进一步改进了一种新的方法,即通过微型气管切开系统,将新鲜气体直接输送到隆突水平,由患者进行呼吸。绵羊通过打开/关闭声门来实现通风。通过这种方式,呼吸的努力大大减少,它不会受到限制。我们相信,上述技术将对重症监护病房的病人管理产生重大影响。-急性呼吸衰竭、机械通气、自主气道压力、释放呼吸机
英文摘要
We have explored in the setting of an experimental animal research laboratory, novel methods and techniques that can improve on patient morbidity and mortality. We have now shown in sheep that periodic tracheal suctioning for the removal of secretions, while intubated and on mechanical ventilation, can be dispensed by using a new method we call Intratracheal Pulmonary ventilation (ITPV), where mucus is continuously entrained through the expiratory air flow, with no need for suctioning. This technique holds promise to greatly improve on tracheal toilet, and patient comfort. We have also further improved on a new method of patient-activated ventilation through a minitracheostomy system, through which fresh gas is delivered directly to the level of the carina. Ventilation is effected by the sheep through opening/closing of the glottis. Through this means, effort of breathing is greatly decreased, it not liminated. We believe that the above techniques will have a significant impact on patient management in the Intensive Care Unit. - Acute Respiratory Failure, Mechanical Ventilation, Spontaneous Airway Pressure, Release Ventilation
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