HIV Prevention Among Adolescent Women

描述（由申请人提供）：本I期可行性研究将 研究与HIV感染行为风险相关的社会心理因素 在青春期女性中。关于这些因素的数据将为制定一项 减少艾滋病毒感染风险的互动式计算机干预措施 艾滋病在年轻女性中在6个月的时间里，第一阶段将 实现三个目标。首先，这项研究将评估行为流行病学， 艾滋病毒感染的风险及其在48名黑人，拉丁裔和 白色青少年女性，年龄11至14岁，在六个赞助 纽约市的社区网站。第二，我们将开发一个原型， 减少艾滋病毒感染和艾滋病风险的互动软件版本 在这些年轻女性中。第三，第一阶段将对原型软件进行试点测试 254名黑人、拉丁裔和白色年轻女性的样本， 合作的纽约市社区网站。在随机设计中， 先导试验包括两组适度的临床试验。营地中的年轻妇女 分配到计算机干预臂将与原型软件交互 在Aim 2中开发。在控制点的年轻妇女将不会得到任何特殊的 干预在计算机干预分娩前后， 两组都将完成一系列结果测量。通过实现其目标， 第一阶段将为第二阶段奠定基础，在第二阶段，我们将全面发展 互动式多媒体产品帮助年轻妇女减少感染艾滋病毒的风险 感染和艾滋病。第二阶段将包括一项随机临床试验， 与来自不同社区环境的年轻妇女一起开发的软件， 大纽约市。如果第二阶段软件成功，第三阶段将 向学校和卫生保健机构传播互动方案， 比如参与这个研发项目的社区机构。 拟议商业应用：不可用

DESCRIPTION (provided by applicant): This Phase I feasibility study will examine psychosocial factors associated with behavioral risks for HIV infection among adolescent women. Data on those factors will inform the development of an interactive computer-based intervention to reduce the risks of HIV infection and AIDS among young women. Over the course of its 6 months, Phase I will accomplish three aims. First, the study will assess the behavioral epidemiology of risks for HIV infection and their reduction among 48 Black, Latina, and White adolescent women, aged 11 through 14 years, under the auspices of six community-based sites in New York City. Second, we will develop a prototype version of interactive software to reduce the risks of HIV infection and AIDS among those young women. Third, Phase I will pilot test the prototype software with a sample of 254 Black, Latina, and White young women through the auspices of the collaborating New York City community sites. In a randomized design, the pilot test involves a modest clinical trial with two arms. Young women in sites assigned to a computer intervention arm will interact with prototypic software developed in Aim 2. Young women in control sites will not receive any special intervention. Before and after computer intervention delivery, all girls in both arms will complete a battery of outcome measures. By meeting its aims, Phase I will lay a foundation for Phase II in which we will fully develop an interactive multimedia product to help young women reduce their risks for HIV infection and AIDS. Phase II will include a randomized clinical trial to test the developed software with young women from various community settings in greater New York City. If Phase II software proves successful, Phase III will disseminate the interactive program to schools and health care facilities and such community agencies as engaged in this R&D project. PROPOSED COMMERCIAL APPLICATION: NOT AVAILABLE