CENTRAL IMMUNOLOGY LAB FOR AIDS VACCINE CLINICAL TRIALS

本合同规定了适应、开发、质量保证、 以及常规的和创新的体液和细胞的表现 免疫学和病毒学评估，对来自 NIAID赞助的多中心艾滋病疫苗临床试验的志愿者。 艾滋病中非人类灵长类动物标本的有限比较分析 疫苗临床前试验、艾滋病毒感染者或志愿者 也进行了非NIAID赞助的候选艾滋病疫苗的试验 由承包商提供。免疫学和病毒学化验数据为 以电子方式传输给艾滋病疫苗评估小组(AVEG) 统计和协调中心进行进一步分析。《校长》 调查员和协查员(S)合作设计和 制定AVEG临床试验方案，提供科学依据 领导疫苗免疫原性的评估。

This Contract provides for the adaptation, development, quality assurance, and performance of routine and innovative humoral and cellular immunologic, as well as virologic evaluations, on specimens from volunteers in NIAID-sponsored multicenter AIDS Vaccine Clinical Trials. Limited comparative assays with specimens from non-human primates in AIDS vaccine preclinical trials, HIV-infected individuals, or volunteers in non-NIAID-sponsored trials of candidate AIDS vaccines are also performed by the Contractor. The immunological and virological assay data is electronically transmitted to the AIDS Vaccine Evaluation Group (AVEG) Statistical and Coordinating Center for further analysis. The Principal Investigator and Co-Investigator(s) collaborate in the design and development of AVEG Clinical Trial Protocols, providing scientific leadership regarding the evaluation of vaccine immunogenicity.