CENTRAL IMMUNOLOGY LAB FOR AIDS VACCINE CLINICAL TRIALS

本合同规定了适应、开发、质量保证、 和常规和创新的体液和细胞的性能 免疫学和病毒学评价， 志愿者在NIAID赞助的多中心艾滋病疫苗临床试验。 用非人灵长类动物标本进行的有限的艾滋病比较试验 疫苗临床前试验、HIV感染者或志愿者 还进行了非NIAID赞助的候选艾滋病疫苗试验 由承包商。 免疫学和病毒学测定数据是 艾滋病疫苗评估小组（AVEG） 统计和协调中心进行进一步分析。 校长 研究者和合作研究者在设计和 制定AVEG临床试验方案，提供科学的 领导疫苗免疫原性评价。

This Contract provides for the adaptation, development, quality assurance, and performance of routine and innovative humoral and cellular immunologic, as well as virologic evaluations, on specimens from volunteers in NIAID-sponsored multicenter AIDS Vaccine Clinical Trials. Limited comparative assays with specimens from non-human primates in AIDS vaccine preclinical trials, HIV-infected individuals, or volunteers in non-NIAID-sponsored trials of candidate AIDS vaccines are also performed by the Contractor. The immunological and virological assay data is electronically transmitted to the AIDS Vaccine Evaluation Group (AVEG) Statistical and Coordinating Center for further analysis. The Principal Investigator and Co-Investigator(s) collaborate in the design and development of AVEG Clinical Trial Protocols, providing scientific leadership regarding the evaluation of vaccine immunogenicity.