INFLUENCE OF SEX HORMONES ON RISK FACTORS FOR HEART DISEASE IN WOMEN WITH NIDDM

本研究旨在调查非胰岛素依赖型糖尿病（NIDDM）女性患者的雄激素水平高于非糖尿病女性，从而增加冠心病风险的假设。本研究将确定有NIDDM发展风险的妇女（患有NIDDM的个体的一级亲属，&/或有妊娠DM史的个体）是否有循环雄激素增加，并将确定胰岛素敏感性（SI）测量与心血管风险之间的关联。

This study is designed to investigate the hypothesis that women with Non-Insulin Dependent Diabetes(NIDDM) have higher androgens when compared to nondiabetic women, to an enhanced risk for CAD. This study will determine whether women at risk for development of NIDDM (1st degree relative of individuals w/NIDDM, &/or with a history of gestational DM) have an increase in circulating androgens and will identify associations between measures of insulin sensitivity (SI) and cardiovascular risk.