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FEEDBACK CONTROL OF GROWTH HORMONE SECRETION

FEEDBACK CONTROL OF GROWTH HORMONE SECRETION
生长激素分泌的反馈控制
批准号:
6122558
负责人:
MICHAEL P WAJNRAJCH
金额:
$12.81万
依托单位国家:
美国
项目类别:
财政年份:
1998
资助国家:
美国
项目状态:
已结题
起止时间:
1998-12-01 至 1999-11-30

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项目成果

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中文摘要
翻译
研究人员继续研究青春期发育与生长激素分泌和对生长激素敏感性的关系。在青春期的男孩和女孩中,IGF-1水平被发现更多地依赖于性激素水平,而不是夜间生长激素的分泌。这种差异不依赖于与青春期相关的IGFBP-1、IGFBP-2或IGFBP-3蛋白的变化。这一发现是在1994年内分泌学会年会上提出的,目前正在准备发表。研究人员继续研究青春期发育与生长激素分泌和对生长激素敏感性的关系。在青春期的男孩和女孩中,IGF-1水平被发现更多地依赖于性激素水平,而不是夜间生长激素的分泌。这种差异不依赖于与青春期相关的IGFBP-1、IGFBP-2或IGFBP-3蛋白的变化。
英文摘要
The Investigators continues to study the relationship between pubertal develop-ment and the secretion of and sensitivity to growth hormone. In adolescent boys and girls IGF-1 levels were found to be more dependent on sex hormone levels than on nocturnal growth hormone secretion. This difference was not dependent on puberty-related changes in the IGF binding proteins IGFBP-1, IGFBP-2, or IGFBP-3. This finding was presented at the Annual 1994 meeting of the Endocrine Society and is being prepared for publication. The Investigators continues to study the relationship between pubertal develop-ment and the secretion of and sensitivity to growth hormone. In adolescent boys and girls IGF-1 levels were found to be more dependent on sex hormone levels than on nocturnal growth hormone secretion. This difference was not dependent on puberty-related changes in the IGF binding proteins IGFBP-1, IGFBP-2, or IGFBP-3.
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会议论文
Molecular Pathophysiology of Human Growth Disorders
Molecular Pathophysiology of Human Growth Disorders
FEEDBACK CONTROL OF GROWTH HORMONE SECRETION
ROLE OF GROWTH HORMONE RELEASING FACTOR IN SHORT STATURE
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