Driverless axons: Steering Regeneration Towards The Light

神经细胞之间的连接缺陷是许多发育障碍的基础，如自闭症和智力迟钝。此外，重建神经细胞连接的缺陷会阻止疾病或创伤后的成功再生。钙对神经细胞至关重要，尤其是在它们生长和连接的过程中。该项目将开发新型光激活工具来操纵钙信号，以控制神经细胞的生长和连接，并增强神经再生。

Defects in the connections between nerve cells underpin many developmental disorders such as autism and mental retardation. Furthermore, defects in re-establishing nerve cell connections prevents successful regeneration after disease or trauma. Calcium is vital to nerve cells, especially as they grow and connect. This project will develop novel light-activated tools to manipulate calcium signals to control nerve cell growth and connectivity and enhance nerve regeneration.