CHEMISTRY STUDIES

该项目开发了新的标签技术，一般适用于 正电子发射氟-18的放射性核素碳-11。在当前 建议强调几个方面。这些领域包括： 1.3种特殊标记脂肪酸的合成与鉴定 各就各位。 2.新型低氧显像剂的评价。 3.碳-11标记的新型标记剂的研制 次氟酸盐作为一种新的合成子和蛋白质和多肽的新途径 具有潜在医学应用的化合物的标记。

This project develops new labeling techniques generally applicable to the positron emitting radionuclides carbon-11 of fluorine-18. In the current proposal several areas are emphasized. These areas are: 1. The synthesis and evaluation of fatty acids labeled in 3 specific positions. 2. The evaluation of a new hypoxic imaging agent. 3. The development of new labeling agents involving carbon-11 labeled hypofluorite as a new synthon and new approaches to protein and peptide labeling of compounds with potential medical application.