CYCLOTRON PRODUCED ISOTOPES IN BIOLOGY & MEDICINE

回旋加速器在生物学中产生的同位素

• 批准号: 6336850
• 负责人: MICHAEL J. WELCH
• 金额: $ 0.21万
• 依托单位: WASHINGTON UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2000
• 资助国家: 美国
• 起止时间: 2000-08-01 至 2001-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6336850
• 关键词: biological products; biomedical resource; carbohydrates; cardiovascular system; endocrine gland /system; human subject; human tissue; male; musculoskeletal system; nutrition; nutrition related tag; physical fitness; proteins; spectrometry

The chemistry core of the cyclotron project is aimed at the development of new radio-pharmaceuticals for use in positron emission tomography. A major usage of the mass spectrometry facility is in the characterization of new compounds. We typically produce new fluorinated or methylated derivatives of lead pharmaceuticals. There are then screened for the desired biological activity. Consequently mass spectrometry plays a fundamental role in this research.

回旋加速器项目的化学核心是针对 开发用于正电子发射的新的放射性药物 断层扫描 质谱分析设备的主要用途是在 新化合物的表征。 我们通常生产新的 先导药物的氟化或甲基化衍生物。 那里 然后筛选所需的生物活性。 因此 质谱分析法在这项研究中起着重要作用。