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CRL 5861 (PURIFIED POLOXAMER 188) IN SICKLE CELL DISEASE & VASO OCCLUSIVE CRISIS

CRL 5861 (PURIFIED POLOXAMER 188) IN SICKLE CELL DISEASE & VASO OCCLUSIVE CRISIS
CRL 5861（纯化的泊洛沙姆 188）治疗镰状细胞病
批准号：
6302992
负责人：
BRIAN K ADLER
金额：
$2.95万
依托单位：
UNIVERSITY OF ALABAMA AT BIRMINGHAM
依托单位国家：
美国
项目类别：
财政年份：
1999
资助国家：
美国
项目状态：
已结题
起止时间：
1999-12-01 至 2000-11-30
来源：
https://reporter.nih.gov/project-details/6302992
关键词：
blood disorder chemotherapy blood vessel occlusion clinical research ethylene oxide human subject human therapy evaluation pathologic process sickle cell anemia

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项目成果

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中文摘要
翻译
由于全国范围内患者应计费用的完成，这项研究已经结束。结果显示了一种强烈的趋势，即该药物缩短了镰状细胞危机的持续时间，但没有达到统计学意义。这种药物的毒性很小。这项研究是一项使用Flocer治疗镰状细胞危象的随机、双盲、安慰剂对照试验。
英文摘要
This study has closed due to completion of patient accrual nationwide. The results demonstrated a strong trend, without reaching statistical significance, for the drug reducing the duration of a sickle cell crisis. Toxicity from the drug was mild. The study was a randomized, double blind, placebo controlled trial of the use of Flocer for the treatment of sickle cell crisis.
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