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WOMENS ANGIOGRAPHIC VITAMIN & ESTROGEN (WAVE) TRIAL

WOMENS ANGIOGRAPHIC VITAMIN & ESTROGEN (WAVE) TRIAL
女性血管造影维生素
批准号：
6302995
负责人：
WILLIAM J ROGERS
金额：
$2.95万
依托单位：
UNIVERSITY OF ALABAMA AT BIRMINGHAM
依托单位国家：
美国
项目类别：
财政年份：
1999
资助国家：
美国
项目状态：
已结题
起止时间：
1999-12-01 至 2000-11-30
来源：
https://reporter.nih.gov/project-details/6302995
关键词：
angiography ascorbate cardiovascular disorder chemotherapy cardiovascular disorder prevention clinical research clinical trials coronary artery estrogens female hormone therapy human subject human therapy evaluation postmenopause tocopherols vitamin therapy

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中文摘要
翻译
WAVE的目的是确定女性激素替代疗法（HRT）或抗氧化维生素（c和E）是否会限制绝经后女性冠状动脉疾病（CAD）的进展。 这项NHLBI-多中心试验将血管造影证实患有CAD的绝经后妇女随机分为HRT组、维生素组或两者均不治疗组。 约3年随访后，受试者将接受重复冠状动脉造影。 将比较基线和随访动脉造影，以评估治疗是否有益。
英文摘要
The purpose of WAVE is to determine if female hormone replacement therapy (HRT) or antioxidant vitamins (c and E) will limit the progression of coronary artery disease (CAD) in post-menopausal women. This NHLBI-multicenter trial has randomized post-menopausal women with angiographicall documented CAD to HRT, vitamins, both or neither. After approximately 3 years follow-up, the subjects will undergo repeat coronary arteriography. The baseline and follow-up arteriograms will be compared to assess if the therapies were beneficial.
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