CORONARY ARTERY DISEASE RISKS IN AMERICAN & KOREAN POST RENAL TRANSPLANTATION

冠状动脉疾病（CAD）是美国肾移植后患者死亡的主要原因（46%）。 肾移植后患者的CAD风险高于一般人群，因为这些患者有预先存在的医疗问题，如糖尿病和高血压，身体活动不足，并正在服用可能进一步增加风险的药物。 韩国肾后患者的CAD风险可能低于美国人，因为他们的饮食摄入量不同，脂肪、饱和脂肪、胆固醇、卡路里和单糖含量非常低。此外，其他营养状况措施，如体重可能会降低韩国肾移植后患者CAD的风险。 然而，其他因素，如高同型半胱氨酸水平或移植后体重增加可能会增加他们的风险。比较韩国和美国肾移植后患者的遗传或环境CAD危险因素将提供有用的比较信息。 这项研究还将有助于制定肾移植后患者的营养干预措施，特别是在韩国，到目前为止几乎没有做过。

Coronary artery disease (CAD) is the leading cause of death (46%) among post-renal transplant patients in the United States. CAD risks among post-renal transplant patients are higher than in the general population because these patients have pre-existing medical problems such as diabetes and hypertension, physical inactivity and are taking drugs which may further increase risks. Korean post-renal patients may have lower CAD risks than Americans because of their different dietary intakes which are very low in fat, saturated fat, cholesterol, calories, and simple sugars. Also, other nutritional status measures such as body weight may decrease risks of CAD among Korean post-renal transplant patients. However other factors such as high homocysteine levels or weight gain after transplant may increase risk among them. A comparison of both genetic or environmental CAD risk factors among Korean and American post-renal transplant patients will provide useful comparative information. The study will also help in crafting nutritional interventions among post-renal transplant patients especially in Korea, where little has been done until now.