补充 LC PUFA 促进生长的配方-猫眼课题宝

补充 LC PUFA 促进生长的配方

批准号：

6309230

负责人：

BRENDA H MORRIS

金额：

$1.11万

依托单位：

UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON

依托单位国家：

美国

项目类别：

财政年份：

1999

资助国家：

美国

项目状态：

已结题

起止时间：

1999-12-01 至 2001-02-28

来源：

https://reporter.nih.gov/project-details/6309230

关键词：

arachidonate clinical research clinical trial phase I developmental nutrition diet therapy dietary supplements growth /development human subject human therapy evaluation infant human (0-1 year) longitudinal human study milk nutrition related tag omega 3 fatty acid premature infant human unsaturated fatty acids

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中文摘要

翻译

美赞臣营养品公司已经开发出以牛奶为基础的配方，其中部分脂质已被二十二碳六烯酸（DHA）和花生四烯酸（ARA）替代。我们推测，这些长链多不饱和脂肪酸（LC PUFA）的添加将改善早产儿的生长发育。本研究是一项两期、双盲、随机、对照、平行设计的前瞻性试验，研究了含有LC PUFA、DHA和ARA的婴儿配方奶粉。本研究的目的是评估喂养添加长链多不饱和脂肪酸（DHA和ARA）的早产儿直至一岁矫正年龄的安全性和有效性。

英文摘要

Mead Johnson Nutritionals has developed milk-based formulas in which part of the lipid has been replaced with sources of docosahexaenoic acid (DHA) and arachidonic acid (ARA). We hypothesize that the addition of these long chain polyunsaturated fatty acids (LC PUFA) will improve the growth and development of preterm infants. This study is a 2-phase, double-blind, randomized, controlled, parallel designed, prospective trial of infant formulas containing the LC PUFA DHA and ARA. The objectives of this study are to evaluate the safety and efficacy of feeding preterm infants formula supplemented with long chain polyunsaturated fatty acids (DHA and ARA) up to one year corrected age.

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