ENERGY RESOLVED DIGITAL HPGE X OR Y-RAY IMAGING DETECTOR

10到150keV光子的成像探测器在医疗技术中有许多用途，包括肿瘤成像、SPECT和放射成像。数字输出特别有用，因为它允许图像增强、分析、传输和存储。在第一阶段，我们提出了一种新技术，可以捕获100微米空间分辨率和1keV或更高能量分辨率的图像。这一能力将促进全新类别的医疗诊断程序，特别是转基因小动物成像。我们的第一阶段工作证明了这种方法的可行性。在这项第二阶段的工作中，我们将与LBNL的Paul Luke合作，建造1厘米厚的交叉条形HPGe探测器，每条具有10 x 10条，每条2 mm x 20 mm。我们将开发具有低噪声和大带宽特性的冷却FET前置放大器，这是这种方法特别需要的。我们还将开发模拟滤波电子设备，以调节探测器的新信号，并使用数字脉冲处理电子设备以高达10/6cps的速率采集这些信号。最后，我们将设计程序来测试探测器的线性，并开发处理算法来完善这一质量。第二阶段将以工作和测试的原型结束。第三阶段将主要涉及生产工程方面的工作。拟议的商业应用：作为一种空间分辨率为100微米的能量分辨数字探测器，拟议的探测器技术可用于许多医疗应用，包括SPECT、小型哺乳动物的能量分辨血管成像、啮齿动物骨骼的骨密度测量以及小型手持伽马相机。非医疗应用将包括无损检测、天体物理伽马成像、核清理用途和X射线衍射探测器。

Imaging detectors for 10 to 150 keV photons have many uses in medical technology, including tumor imaging, SPECT, and radiography. Digital output is particularly useful since it allows image enhancement, analysis, transmission and storage. In Phase I we proposed a new technology that could capture images with 100 microm spatial resolution and 1 keV energy resolution or better. This capability would facilitate entirely new classes of medical diagnostic procedures, particularly for transgenic small animal imaging. Our Phase I work demonstrated the feasibility of this approach. In this Phase II effort, collaborating with Paul Luke at LBNL, we will construct 1 cm thick crossed-strip HPGe detectors having 10 x 10 strips, each 2 mm x 20 mm. We will develop cooled FET preamplifiers having low noise and large bandwidth properties specifically required by this approach. We will also develop analog filtering electronics to condition the detector's novel signals and employ digital pulse processing electronics to acquire these signals at rates up to 10/6 cps. Finally, we will devise procedures to test the detector's linearity and develop processing algorithms to perfect this quality. Phase II will conclude with a working and tested prototype. Phase III will entail primarily production engineering efforts. PROPOSED COMMERCIAL APPLICATION: As an energy resolved digital detector with 100 microm spatial resolution, the proposed detector technology could find many medical applications, including SPECT, energy resolved angiography for small mammals, bone densitometry on rodent bones, and small, hand-held gamma cameras. Non-medical applications would include non-destructive testing, astrophysical gamma imaging, nuclear cleanup uses, and x-ray diffraction detectors.