RES FACIL IMPROVEMENT: NEUROSCIENCE ALZHEIMER

描述（由申请人提供）：拟议项目是对华盛顿大学健康科学中心（WaRPRC） I-Wing的七楼进行大规模重建，以创建专业研究实验室、动物住房、手术室和办公空间，这些空间是利用NHPs进行技术创新神经科学研究所必需的。WaRPRC的长期目标是追求和支持使用NHPs的重要生物医学研究，并开发创新和专门资源，以促进将NHPs用作研究模式。WaRPRC的一个关键组成部分是神经科学部门的杰出专业知识，该部门由六名核心员工和五个中心研究附属机构组成，并由内部实验动物服务、生物工程和生物结构技术设施提供支持。为了跟上认知神经科学研究的爆炸式增长，计划建立一个新的CCN。CCN的任务将是利用神经活动定量分析的新技术来研究NHPs中高级功能的神经机制。重建的设施将为灵长类中心的两名核心工作人员和一个神经计算实验室创建实验室，并支持正电子发射断层扫描（PET）成像设施。CCN还将包括WaRPRC中从事认知工作的其他神经科学家，并将促进校园范围内与众多部门的合作。

DESCRIPTION (provided by applicant): The proposed project is to extensively reconstruct the seventh floor of the I-Wing in the University of Washington Health Sciences Center, WaRPRC to create, the specialized research laboratories, animal housing, procedure rooms, and office space necessary to conduct technically innovative neuroscience research utilizing NHPs. The long-term goal of the WaRPRC is to pursue and support important biomedical research using NHPs, and to develop innovative and specialized resources to facilitate the use of NHPs as research models. A key component of the WaRPRC is the outstanding expertise of the Neuroscience Division, comprised of six Core Staff and five Center-based Research Affiliates, supported by in-house laboratory animal services, bioengineering and a biostructure technology facility. To keep pace with the explosive growth of research in cognitive neuroscience it is planned to establish a new CCN. The mission of the CCN will be to investigate neural mechanisms of higher functions in NHPs using new technologies for quantitative analysis of neural activity. The reconstructed facility will create laboratories for two Primate Center Core Staff scientists and a Neural Computation laboratory and support a Positron Emission Tomography (PET) imaging facility. The CCN will also encompass other neuroscientists in the WaRPRC pursuing cognitive work and will facilitate campus-wide collaborations with numerous departments.