COLLABORATIVE PROSPECTIVE STUDY OF VERTICAL TRANSMISSION OF HIV

妇女和婴儿传播研究，其目的是开始了解艾滋病毒传染给风险母亲的子女的频率;进行早期诊断;了解感染艾滋病毒的儿童如何生长和发育;以及在有治疗方法时进行早期干预。 目前，在儿童医院的WITS中积极跟踪了82名婴儿和儿童。世界综合贸易调查研究开始在广泛的学科范围内得出一些调查结果。初步研究结果很有趣，可能对咨询孕妇有用。以下是WITS产生的研究领域：1）影响HIV-1传播的产科因素; 2）垂直传播的免疫学和病毒学相关性; 3）干血斑标本的使用和PCR检测HIV的诊断价值;以及4）HIV感染妇女所生婴儿的身体生长自然史。

Women and Infants Transmission Study (WITS), the purpose of which is to begin to understand how often HIV is passed on to children of risk mothers; to make early diagnosis; to understand how children with HIV infection grow and develop; and to allow early intervention as therapies become available. Currently, 82 infants and children are actively followed in WITS at Children's Hospital. A number of findings over a broad spectrum of disciplines has begun to emerge from the WITS study. The preliminary findings are interesting and may possibly be useful for counseling pregnant women. The following are research areas resulting from WITS: 1) obstetrical factors which influence HIV-1 transmission; 2) immunologic and virologic correlates of vertical transmission; 3) use of dried blood spot specimens and the diagnostic value of PCR for detection of HIV, and 4) natural history of somatic growth in infants born to HIV infected women.