International Prader-Willi Syndrome Scientific Meeting

描述(申请人提供)：Prader-Willi综合征(PWS) 是研究各种常见临床问题的理想模型 如肥胖、强迫症、低眼压和智力低下。 这种神经行为综合征的遗传位置已经缩小到2 染色体15q11-q13上的MB区。此外，工务局局长与 Angelman综合征(AS)代表了基因组印记的最好例子 人类。正常印记过程的中断已被证明是 参与了许多出生缺陷、遗传性疾病和 癌症。 国际Prader-Willi综合征组织(IPWSO)成立于#年 1991年。第四届三年期会议将于#年在明尼苏达州圣保罗举行。 2001年6月。它将由单独的Science、Provider和Parent组成 会议。科学会议将于2001年6月27日至29日举行。 单独的科学会议将包括遗传学、生长激素、肥胖 和新陈代谢、内分泌学、心理学和精神病学、动物模型和 医疗和牙科问题。每节课将邀请一到两人参加 “最先进的”演讲者，以及从应邀中挑选的演讲者 摘要。预计的受众范围将从 临床和基础科学给年轻的研究人员开始新的 从事研究工作。这项申请将为年轻人提供旅行津贴。 调查人员(即研究生和医学生、住院医生、博士后 研究员和初任教员)介绍他们的研究。私营企业 将寻求支持，为“最先进”演讲者提供旅行。

DESCRIPTION (provided by applicant): The Prader-Willi syndrome (PWS) represents an ideal model in which to study various common clinical problems such as obesity, obsessive-compulsiveness, hypotonia, and mental retardation. The genetic location of this neurobehavioral syndrome has been narrowed to a 2 MB region on chromosome 15q11-q13. In addition, PWS together with the Angelman syndrome (AS) represent the best examples of genomic imprinting in humans. Disruption of the normal imprinting process has been shown to be involved in the etiology of a number of birth defects, genetic diseases, and cancers. The International Prader-Willi Syndrome Organization (IPWSO) was founded in 1991. The fourth triennial conference will be held in St. Paul, Minnesota in June 2001. It will be comprised of separate Scientific, Provider, and Parent Conferences. The Scientific Conference will run from June 27-29, 2001. Separate scientific sessions will include Genetics, Growth Hormone, Obesity and Metabolism, Endocrinology, Psychology and Psychiatry, Animal Models, and Medical and Dental Issues. For each session there will be one to two invited "State of the Art" speakers, as well as speakers selected from solicited abstracts. The expected audience will range from established investigators in the clinical and basic sciences to young investigators embarking on new research careers. This application will provide travel stipends for the young investigators (i.e., graduate and medical students, residents, postdoctoral fellows, and beginning faculty) to present their research. Private industry support will be sought to provide travel for the "State of the Art" speakers.