Functions of Antioxidant Nutrients and Phytochemicals

描述（改编自应用程序） 这是一份关于“生理学”会议部分资金的申请 抗氧化营养素和植物化学物质的功能”。这次会议将是 6月16日至21日在亚利桑那州图森市的Omni度假村举行， 2001.本次会议是三个非常成功的FASEB夏季的续集 研究会议上的抗氧化剂，并借鉴了越来越多的认识， 细胞氧化状态的改变可导致许多生物化学反应， 变化和不平衡。这些不平衡与老龄化和 增加各种慢性疾病的风险，包括癌症，心脏病， 糖尿病和神经退行性疾病。为了更好的靶向抗氧化剂 或植物化学疗法在各种疾病的过程中，它是关键， 了解这些生物因子的基本作用机制。这次会议 将提出一个当代的分子生物学，生物化学， 抗氧化剂和植物化学物质的生理作用机制，以及 as their其role作用in cell细胞biology生物.会议的一个新方面是增加了 科学家评估氧化平衡在增殖中的作用， 生殖和胚胎发生过程中的细胞凋亡。了解这些关键 过程在整个生命周期中至关重要。约160名参与者 将从最有可能分享新信息的科学家中选出， 为促进思想交流做出贡献。演讲者或海报展示者 将是最近取得重大成就的人。会议主要议题 将是：1）抗氧化剂和衰老; 2）DNA损伤：来源，修复和 抗氧化剂的调节; 3）类胡萝卜素与健康; 4）抗氧化剂与基因 调节; 5）黄酮类化合物的健康作用; 6）抗氧化剂和 动脉粥样硬化; 7）维生素E的作用; 8）性和抗氧化剂;和9）口服 展示精选海报。此外，还有两张为期两天的海报。 介绍。这次会议将提供一个论坛，鼓励对话 来自不同学科的贡献者之间。聚合结果 应该是这个快速发展的领域的当代视角和概述。 这一概述应允许评估未来的研究方向，以及 对近期研究的评论。

DESCRIPTION (adapted from the application) This is an application for partial funding of a conference on "Physiological Functions of Antioxidant Nutrients and Phytochemicals". This conference will be held under the auspices of FASEB at the Omni Resort, Tucson, AZ on June 16-21, 2001. This conference is a sequel to three very successful FASEB Summer Research Conferences on antioxidants and draws upon a growing awareness that alterations in the oxidative state of cells can lead to many biochemical changes and imbalances. These imbalances are associated with aging and with an increased risk of various chronic diseases, including cancer, heart disease, diabetes and neurodegenerative diseases. In order to better target antioxidant or phytochemical therapies in the various disease processes, it is pivotal to understand the basic mechanisms of action of these biofactors. This conference will present a contemporary view of molecular biological, biochemical, and physiological mechanisms of action of antioxidants and phytochemicals, as well as their role in cell biology. A novel aspect of conference is the addition of scientists evaluating the role of oxidative balance in proliferation and apoptosis during reproduction and embryogenesis. Understanding these key processes is essential through out the lifespan. Approximately 160 participants will be chosen from among scientists most likely to share new information and to contribute to stimulating exchanges of ideas. Speakers or poster presenters will be persons with significant recent achievements. The major session topics will be: 1) antioxidants and aging; 2) DNA damage: sources, repair and modulation by antioxidants; 3) carotenoids and health; 4) antioxidants and gene regulation; 5) health effects of flavonoids; 6) antioxidants and atherosclerosis; 7) vitamin E actions; 8) sex and antioxidants; and 9) oral presentations of selected posters. There will also be two 2-day poster presentations. This conference will provide a forum and encourage dialogue between contributors from a broad variety of disciplines. The aggregate result should be a contemporary perspective and overview of this rapidly moving field. This overview should allow evaluation of future research directions, as well as critical review of the recent research.