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PATHOGENESIS OF PRIMARY HIV INFECTION

PATHOGENESIS OF PRIMARY HIV INFECTION
原发性 HIV 感染的发病机制
批准号：
6306702
负责人：
ERIC S DAAR
金额：
$0.1万
依托单位：
LUNDQUIST INSTITUTE FOR BIOMEDICAL INNOVATION AT HARBOR-UCLA MEDICAL CENTER
依托单位国家：
美国
项目类别：
财政年份：
1999
资助国家：
美国
项目状态：
已结题
起止时间：
1999-12-01 至 2000-11-30
来源：
https://reporter.nih.gov/project-details/6306702
关键词：
HIV infections clinical research disease /disorder etiology human immunodeficiency virus human subject pathologic process virus load

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中文摘要
翻译
这项研究的目的是为了更好地确定原发(急性)艾滋病毒感染的自然历史。新感染艾滋病毒的患者经常发展为急性单核细胞增多症样疾病。已经证明，在这种急性疾病发生时，这些人中的许多人的血液中都有高水平的病毒。将广泛跟踪患者的免疫系统变化和病毒载量的变化。患者招募正在进行中，GCRC实验室进行实验室研究的淋巴细胞分离。
英文摘要
The purpose of this study is to better define the natural history of primary (acute) HIV infection. Patients who are newly infected with HIV frequently develop an acute mononucleosis-like illness. It has been demonstrated that many of these people have high levels of virus in their blood at the time of this acute illness. Patients will be followed extensively for changes in the immune system and for changes in viral load. Patient recruitment is ongoing, and isolation of lymphocytes for laboratory investigation is performed by the GCRC laboratory.
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