NEUROBIOLOGY AND NEUROPSYCHOLOGY OF AGING

描述（从应用程序）：这个培训计划已经开发，以提供博士前学生和博士后研究员在衰老的神经生物学和神经心理学的具体培训。该提案的核心是将两个长期存在的NIA计划项目的调查人员的专业知识合并起来。一个是关注人类在健康和疾病方面的衰老（AG-04953）在建议的培训补助金的主管之一Marilyn Albert博士的指导下，以马萨诸塞州总医院（MGH）为中心，另一个在非人灵长类动物模型中认知下降的神经基础上进行（AG-00001），中心位于波士顿大学医学院（BUSM），其中另一位主任Moss博士是共同主要研究者。培训将侧重于研究领域，包括人类和动物模型正常衰老的神经心理学和神经生物学，与年龄有关的痴呆症和神经系统疾病;神经遗传学和神经流行病学;以及与年龄有关的细胞和突触超微结构变化的研究和其他相关主题。有六名培训师在波士顿大学医学院，三名在哈佛医学院，四名在BUSM附属退伍军人管理医院。该计划包括深入的课堂教学，动手实验室研究，互动网站，年度实地考察和务虚会，以及13名教师正在调查的神经生物学和神经心理学领域的一个或多个经验。此外，学生和研究员将参加一系列关于老龄化的研讨会在BUSM和MGH，以扩大他们的当代老龄化研究的知识。还将鼓励受训人员参加教学，为他们担任学术教师职位做好准备。所有学员的课堂教学围绕团队讲授衰老的神经生物学和神经心理学入门课程，神经科学课程，以及由哈佛医学院衰老司举办的衰老夏季研讨会系列。这些课程和研讨会包括讲座，讨论，研究论文和实验室演示的批评。

DESCRIPTION (From the application): This training program has been developed to provide predoctoral students and postdoctoral fellows with specific training in the Neurobiology and Neuropsychology of Aging. At the core of this proposal is the merging of the expertise of investigators from two long standing NIA program projects. One is focused on human aging in health and disease (AG-04953) centered at Massachusetts General Hospital (MGH) under the direction of Dr. Marilyn Albert, one of the directors of the proposed training grant, and the other on the neural basis of cognitive decline in a non-human primate model (AG-00001) centered at Boston University School of Medicine (BUSM) of which Dr. Moss, the other director, is Co-PI. The training will focus on areas of research that include the neuropsychology and neurobiology of normal aging in humans and animal models, age-related dementia and neurologic disease; neurogenetics and neuroepidemiology; and studies of age-related changes in cellular and synaptic ultrastructure and other related topics. There are six trainers based at Boston University School of Medicine, three based at Harvard Medical School and four based at BUSM affiliated Veterans Administration Hospitals. The program includes in-depth classroom instruction, hands-on laboratory research, interactive web-site, annual field trip and retreat, and experience in one or more of the areas of the neurobiology and neuropsychology of aging being investigated by the 13 faculty. Additionally, students and fellows will attend a series of seminars on aging at BUSM and at MGH to broaden their knowledge of contemporary aging research. Trainees will also be encouraged to participate in teaching to prepare them for academic faculty positions. Class instruction for all trainees centers around the team taught introductory course in the Neurobiology and Neuropsychology of Aging, a course in Neuroscience, and a summer seminar series on Aging conducted by the Division on Aging at Harvard Medical School. These courses and seminars consist of lectures, discussions, critiques of research paper and laboratory demonstrations.