TRAINING IN IMMUNODERMATOLOGY

描述（由申请人提供）：大卫诺里斯医学博士。将成为PI， 现任培训副主任威廉·韦斯顿医学博士假设一位高级顾问 作用诺里斯博士将继续发展合作互动 这对未来的机构培训至关重要。过去三 26名毕业生中有24人进入全日制学术生涯， 目前保留在全职学术皮肤科。还有一个在 训练培训教师将扩大到9个医学博士。博士学位培训 教师包括更多的资深科学家，包括细胞和 结构生物学，丹佛自体免疫中心主任和 人类医学遗传学的负责人和过敏杂志的现任编辑 临床免疫学以前在教育部实习的主管 免疫学，药理学系和流变学系，医学 包括内科的肿瘤学和传染病学。 每个培训学院都有独立的资金（2001 - 02年度为1 540万美元， 他们都成功地指导了过去的学员， 学术生涯。感兴趣的研究领域包括：皮肤分子 病毒学、黑素细胞生物学、分子遗传学、黑色素瘤、非黑色素瘤皮肤 癌症、癌基因、细胞毒性机制和程序性细胞死亡， 白三烯，细胞因子包括IL 1，T细胞受体，光免疫学，细胞 信号传导和细胞表面受体。提供的设施和设备 学员已升级。到2003年，受训人员将迁往新大学 科罗拉多癌症研究大楼，拥有超过7,000个潮湿的实验室空间 可用于计划的皮肤科部分， 在癌症中心。 建议两个博士。和医学博士候选人包括两名 每年招收的学员。所有的受训者都应该证明他们是 有能力从事学术皮肤病学或皮肤生物学的职业。四 培训的要点提出：正式的课程工作，研讨会，个人 研究项目和交流技能培训。特别强调 免疫学，分子生物学，分子遗传学， 细胞生物学，科学伦理学，生物统计学和危险物质管理 废物被提出。学员将选择自己感兴趣的项目或从 在培训主管向他们提出的广泛名单中。通信 将强调受训人员的技能， 由李和韦斯顿博士监督写作和演示。

DESCRIPTION (provided by applicant): David Norris M.D. will become the PI with the current training Co-director, William Weston M.D. assuming a senior advisor role. Dr. Norris will continue to develop the collaborative interactions critical to this institutional training grant in the future. In the past three training periods 24 of 26 graduates entered full time academic careers and 18 are currently retained in full time academic dermatology. There is one still in training. The training faculty will be enlarged to 9 M.D. & 3 Ph.D. training faculty to include more senior scientists including the Chairman of Cell and Structural Biology, the Director of the Denver Autoinimunity Center and the Head of Human Medical Genetics and the current Editor of the Journal of Allergy and Clinical Immunology. Previous trainee supervisors in the Department of Immunology, the Department of Pharmacology & Divisions of Rheumatology, Medical Oncology and Infectious Diseases of the Department of Medicine are included. The training faculty each have independent funding ($15.4 million for 2001-02, and have each demonstrated successful mentoring of past trainees leading to academic careers. Research areas of interest include: cutaneous molecular virology, melanocyte biology, molecular genetics, melanoma, nonmelanoma skin cancer, oncogenes, cytotoxic mechanisms and programmed cell death, leukotrienes, cytokines including IL1, T cell receptors, photoimmunology, cell signaling and cell surface receptors. Facilities and equipment available to trainees have been upgraded. By 2003, trainees will move to the new University of Colorado Cancer research building with over 7,000 of wet laboratory space available for the dermatology portion of the program with immediate adjacency within the Cancer Center. It is proposed that both Ph.D. and M.D. candidates be included with two trainees recruited each year. All trainees should have demonstrated they are capable of a career in academic dermatology or cutaneous biology. Four essentials of training are proposed: Formal course work, seminars, individual research projects and training in communications skills. Special emphasis on formal coursework in Immunology, Molecular Biology, Molecular Genetics, Cellular Biology, Scientific Ethics, Biostatistics and Management of Hazardous waste is proposed. Trainees will select a project of their own interest or from among a broad list presented to them by the training supervisors. Communication skills of the trainees will be emphasized with specific training in scientific writing and presentations supervised by Drs. Lee & Weston.