CORE--BIOSTATISTICS

口腔健康综合研究中心(COHRCD)涉及从临床前研究到转化研究、临床和行为干预试验、有效性研究和卫生服务研究等一系列项目。生物统计和研究设计(BARD)核心将为每项研究量身定做支持，因为每个项目都有具体的研究设计和统计分析需求。巴德核心将为COHRCD的所有项目和调查人员提供建议、教育和统计咨询。巴德核心将继续与调查人员合作，完善协议和数据收集工具，最终确定随机化时间表、数据管理、监测、质量控制和可靠性的计划；协调整合不同项目的数据库，以实现更强大、更独特的多变量分析；为基线、中期和最终分析提供统计咨询；教育研究人员如何为他们的研究设计和分析选择统计方法，以及如何解释结果；促进在加州大学旧金山分校牙科诊所开发更全面的电子患者记录数据库；并通过无墙临床研究中心，促进以试点项目、主要研究的中期成果以及住院医生、研究生、博士后研究员和教师的相关努力为基础的高质量研究的发展。应该像研究过程中的任何其他步骤一样，在研究的数据分析方面投入足够的时间和精力。博士级别的巴德核心人员拥有70多人-年的合作研究经验，能够充分满足这些需求。

The Comprehensive Oral Health Research Center of Discovery (COHRCD) involves projects ranging from pre-clinical studies to translational studies, clinical and behavioral intervention trials, effectiveness research, and health services research. The Biostatistical and Research Design (BARD) Core will tailor support for each study, since each project has specific research design and statistical analysis needs. The BARD Core will provide advice, education, and statistical consulting to all COHRCD projects and investigators. The BARD Core will continue to work with investigators to refine protocols and data collection instruments, will finalize plans for randomization schedules, data management, monitoring, quality control and reliability; coordinate integrating databases from different projects to enable more powerful, unique multivariate analyses; provide statistical consulting for baseline, interim, and final analyses; educate researchers about selecting statistical methods for their research design and analyses and about interpreting the results; foster developing a more comprehensive electronic patient record database in the UCSF School of Dentistry clinics; and promote the development of quality research studies based on pilot projects, on intermediate results on major studies, and on related endeavors from residents, graduate students, postdoctoral fellows, and faculty via the Clinical Research Center without Walls. Sufficient time and effort should be given to the data analytic aspects of research, as with any other step in the research process. The doctoral level BARD Core personnel have over 70 person-years of collaborative research experience and can adequately fulfill those needs.