MBRS PROGRAM

德克萨斯农工大学金斯维尔分校的N.I.H.-M.B.R.S.项目包括 以下是主要目标：(1)建立和支持 TAMUK适宜的生物医学研究环境；(2)吸引、培育 并鼓励学生通过参与 六位首席调查人员的研究项目 提交的研究建议的核心；(3)提供适当的 允许参与者调查人员检查密钥的基础设施 生物医学研究的各个方面(特别是生物和化学研究 科学)；和4)提供大量有意义的数据和信息 关于生物医学的相关性和重要性的问题。 这六个新项目的范围和适用范围各不相同 生物医学问题。第一个问题主要考察 单纯疱疹病毒的转录调控及其作用机制 病毒潜伏期和重新激活。第二个项目将阐明该角色 子宫特异性生长因子对胎儿造血的影响及作用 在细胞分化时。第三个项目包括一个详细的 果蝇乙醚-a-go-go相关基因(Derg)的特征 转录调控水平上的钾通道以及 猪细小病毒第二位点修饰基因的分离与鉴定 德尔格突变。第四个项目包括对响尾蛇毒液的研究。 以及蛇毒金属蛋白酶和金属蛋白酶的功能特性。 新型哺乳动物抗出血素。第五个项目考查生物 节律与生殖状态和能量的调节作用 新陈代谢。第六个项目研究了新的酪氨酸激酶介导的 福氏志贺菌中参与和促进的信号通路 这种特殊病原体的侵袭性。 这六个项目支持两个不同部门的研究 为参与的教员提供理想的机会来扩大和 加强他们的个人研究计划。该中心的研究目标 个别调查人员也将为 对本科生和研究生进行重点方面的培训 生物医学研究以及为未来职业生涯做好适当准备 生物医学研究，特别是在生物和化学科学方面。

The N.I.H.-M.B.R.S. program at Texas A&M university-Kingsville consists of the following primary objectives: (1) establish and provide support for an appropriate biomedical research environment at TAMUK; (2) attract, nurture and encourage students to pursue research careers through participation in the research projects of the six principal investigators that comprise the core of the submitted research proposals; (3) provide a suitable infrastructure that permits participant investigators to examine key aspects of biomedical research (in particular the biological and chemical sciences); and 4) provide substantial and significant data and information regarding questions of biomedical relevance and importance. The six new projects are diverse in their scope and application to biomedical questions. The first question primarily examines the transcriptional control of the Herpes simplex virus and the mechanisms of viral latency and reactivation. The second project will elucidate the role of uterine-specific growth factors upon fetal hematopoiesis and effects upon cell differentiation. The third project consists of a detailed characterization of the Drosophila ether-a-go-go related gene (dERG) potassium channel at the levels of transcriptional control as well as genetic isolation and characterization of second-site modifiers of the dERG mutation. The fourth project consists of a study of rattlesnake venom and the functional characterization of snake venom metalloproteinases and novel mammalian antihemorrhaghins. The fifth project examines biological rhythms and the modulatory effects of reproductive status and energy metabolism. The sixth project examines novel tyrosine kinase-mediated signaling pathways in Shigella flexneri that participate and contribute to the invasiveness of that particular pathogen. The six projects support research in two different departments that provide ideal opportunities for the participant faculty to expand and enhance their individual research programs. The research goals of the individual investigators will also provide excellent opportunities for the training of undergraduate and graduate students in key aspects of biomedical research as well as suitable preparation for future careers in biomedical research, particularly in the biological and chemical sciences.