MBRS SCORE Program at Texas A&M University-Kingsville

描述（由申请人提供）：MBRS SCORE计划在得克萨斯A&M大学金斯维尔包括以下主要目标：（1）建立和提供支持，为适当的生物医学研究环境在TAMUK;（2）提供一个合适的基础设施，允许参与研究人员检查生物医学研究的关键方面;以及（3）提供关于生物医学相关性和重要性问题的大量和重要的数据和信息。 目前资助的四个项目包括细胞凋亡，神经遗传学，毒液去整合素作用和视神经再生。该提案中描述的八个补充项目包括新药设计方法、营养状况和骨密度损失、神经系统中的瘦素信号传导、西尼罗河病毒传播、新出现的人畜共患疾病、受母体影响的应激反应、柑橘类植物的天然产物以及生殖-促生长相互作用。 除了目前资助的四个项目外，这八个新项目将共同支持五个不同部门的研究，并为参与教师提供理想的机会，以扩大和加强他们的个人研究计划。个人研究者的研究目标也将为本科生和研究生在生物医学研究的关键方面的培训提供极好的机会，并为生物医学研究的未来职业生涯做好适当的准备。

DESCRIPTION (provided by applicant): The MBRS SCORE program at Texas A&M University-Kingsville consists of the following primary objectives: (1) establish and provide support for an appropriate biomedical research environment at TAMUK; (2) provide a suitable infrastructure that permits participant investigators to examine key aspects of biomedical research; and (3) provide substantial and significant data and information regarding questions of biomedical relevance and importance. The four currently funded projects encompass apoptosis, neurogenetics, venom disintegrin action, and optic nerve regeneration. The eight supplemental projects described in this proposal encompass novel drug design approaches, nutritional status and bone density loss, leptin signaling in the nervous system, West Nile Virus transmission, emerging zoonotic diseases, maternal-affected stress responses, natural products derived from citrus plants, and reproductive-somatotropic interactions. Together these eight new projects, in addition to the four currently funded projects, will support research in five different departments and provide ideal opportunities for the participant faculty to expand and enhance their individual research programs. The research goals of the individual investigators will also provide excellent opportunities for the training of undergraduate and graduate students in key aspects of biomedical research as well as suitable preparation for future careers in biomedical research.