Novel computational tools for elucidating evolutionary consequences of reticulation events (WU_U17DTP)

重组、杂交和水平基因转移（HGT）导致网状进化，这些进化力量共同成为适应性新颖性的主要来源，因为它们瞬间（即在一代人中）引入了大量新的遗传变异。随着下一代测序技术的出现，网状进化的特征被发现在生命王国中无处不在，但随着大数据分析的复杂性增加，识别和分析其在基因组中的足迹在计算上具有挑战性。引用:1。Huber et al.（2015）系统生物学[j]。Oldman et al. (2016) Molecular Biology and Evolution3。McMullan et al. (2016) Elife4。Jouet et al.（2015）分子生态学

Recombination, hybridization, and horizontal gene transfer (HGT) lead to reticulate evolution, and together, these evolutionary forces are one principal source for adaptive novelty because they introduce a vast amount of novel genetic variation instantly (i.e. in one generation). With the advent of Next Generation Sequencing technologies, the signature of reticulate evolution is found to be ubiquitous across the kingdoms of life, but with the increase complexity of BIG DATA analysis, identifying and analysing its footprint in genomes is computationally challenging. References:1. Huber et al. (2015) Systematic Biology2. Oldman et al. (2016) Molecular Biology and Evolution3. McMullan et al. (2016) Elife4. Jouet et al. (2015) Molecular Ecology