North Carolina Family Practice PBRN

描述（由申请人提供）：北卡罗来纳州家庭实践实践为基础的研究网络（NCFP-PBRN）提出了进一步的基础设施发展（第一类）和4个探索/试点项目（第二类），以响应AHRQ RFA #HS-02-003。全国家庭康复方案-PBRN由16个家庭康复中心组成，构成了国家康复机构的分层（农村/城市、地区）样本。它由北卡罗来纳州大学家庭医学系和瑟斯顿关节炎研究中心在疾病控制与预防中心为期2年（2000-2002年）的资助下创立，并提供补充机构资金以加强少数族裔招募。最初的资金用于研究关节炎的补充和替代药物使用;然而，从一开始，NCFP-PBRN的结构就旨在促进广泛的基于初级保健的研究，围绕一组有代表性的实践和基于实践的成年患者队列。NCFP-PBRN已招募并目前正在维持一个约4，500名成人患者的队列，这些患者于2001年从参与实践中招募。目前正在使用这一队列数据的论文涉及老年人抑郁症的患病率、种族与健康相关生活质量之间的关系以及关节炎患者使用补充和替代疗法的情况。 拟议的项目将通过加强项目基础设施和沟通，并通过支持具有很大潜力的试点研究，使国家森林合作项目-PBRN能够进一步发展其使命，并在实现自我可持续性方面取得进展，从而导致资助将研究成果转化为实践的项目。目标包括：（1）发展研究协调的程序和人员，（2）加强沟通联系，（3）征聘四个以少数群体为重点的做法，（4）开发社区健康指标数据库，（5）进行四项试点研究。拟议试点研究的主题包括II型糖尿病高风险人群的身体活动、老龄化和慢性病中的性健康问题、初级保健中的临终规划以及对生物恐怖主义的监测。拟议的试点研究中有三项旨在确定将研究证据应用于实践的有效战略;第四项将对少数群体人口形成宝贵的见解。

DESCRIPTION (provided by applicant): The North Carolina Family Practice Practice-Based Research Network (NCFP-PBRN) proposes further infrastructure development (Category I) and 4 exploratory/pilot projects (Category II), in response to AHRQ RFA #HS-02-003. The NCFP-PBRN consists of 16 family practice sites, which constitute a stratified (rural/urban, region) sample of the state's practice settings. It was founded by the Department of Family Medicine and the Thurston Arthritis Research Center at the University of North Carolina under a 2-year (2000-2002) grant from the Centers for Disease Control and Prevention, with supplemental institutional funding to enhance minority recruitment. Initial funding was awarded to study complementary and alternative medicine use in arthritis; however from its outset the NCFP-PBRN was structured with the intention of fostering a wide range of primary care-based studies, centered around a representative group of practices and a practice-based cohort of adult patients. The NCFP-PBRN has enrolled and is currently maintaining a cohort of approximately 4,500 adult patients who were recruited in 2001 from participating practices. Papers currently in process using data from this cohort address the prevalence of depression in older persons, the relationship between race and health-related quality of life, and use of complementary and alternative therapies by persons with arthritis. The proposed project will enable the NCFP-PBRN to further develop its mission and progress toward self sustainability by strengthening project infrastructure and communication, and by supporting pilot studies with high potential for leading to funded projects that translate research findings into practice. Aims include: 1) development of processes and personnel for research coordination, 2) enhancement of communication linkages, 3) recruitment of four minority-focused practices, 4) development of a community health indicators database, and 5) conducting four pilot studies. Topics of proposed pilot studies include physical activity in persons at high risk for type II diabetes, sexual health problems in aging and chronic illness, end-of-life planning in primary care, and surveillance for bioterrorism. Three of the proposed pilot studies seek to identify effective strategies to apply research evidence to practice; the fourth will develop valuable insights into minority populations.