CORE--TISSUE PROCESSING FACILITY

组织处理中心将负责协调拟议计划项目中人体组织分散的所有方面。组织处理核心将由核心总监Anthony A. Gaspari，医学博士; Robert Rose，博士; Glynis Scoot，医学博士，顾问和技术助理Carol Tanck女士。核心研究的具体目的是：1）招募患有外生殖器疣的受试者以获得疣组织2）用于体外免疫学研究的疣浸润淋巴细胞的回收和扩增。3)外周血淋巴细胞的处理和储存。4)血清样本的处理和储存。5)通过DNA PCR-ELISA进行HPV基因分型6）从HPV感染组织制备自体HPV疫苗。7)协调将组织分发给适当的研究者。

The Tissue Processing Core will be responsible for the coordination of all aspects of dispersing human tissues for the proposed program project. The Tissue Processing Core will be composed of the Core Director, Anthony A. Gaspari, MD; Robert Rose, PhD, Glynis Scoot, MD, Consultant, and a technical associate, Ms. Carol Tanck. The Specific Aims of the core will be to: 1) Recruit subjects with external genital warts to obtain wart tissue 2) Recovery and expansion of wart-infiltrating lymphocytes for in vitro immunologic studies. 3) Processing and storage of peripheral blood lymphocytes. 4) Processing and storage of serum samples. 5) HPV Genotyping by DNA PCR-ELISA 6) Preparation of autologous HPV vaccine from HPV infected tissue. 7) Coordinate distribution of tissues to appropriate investigators.