Design of a Compact Cyclotron for Proton Therapy

超导回旋加速器正在成为现代质子放射疗法的支柱，有几家公司现在提供基于使用230 - 250 MeV输出回旋加速器的治疗解决方案，适用于成人治疗中的深层肿瘤。然而，使用这些大型回旋加速器输送30至70 MeV的低能质子在技术上存在问题，需要一种较低能量的设计（例如适用于眼部治疗和其他浅层治疗）;克拉特布里奇癌症中心开发了世界上第一个医院质子治疗服务的任何一种，但现在正在寻找取代其机器更现代，在安泰亚科技的协助下，安泰亚是一家加速器开发公司，在设计医用回旋加速器方面拥有世界领先的经验。本博士项目将利用安泰亚的经验和技术平台，并将其应用于Clatterbridge的临床要求，以开发回旋加速器设计和相关的射束输送系统，旨在替代Clatterbridge的现有治疗系统。成功的候选人将在Cockcroft研究所（柴郡，英国，从事束流输送设计），Clatterbridge癌症中心（维拉尔，英国，进行测量和制定临床规范）和Antaya科技开发机构（新罕布什尔州，美国，从事回旋加速器设计）之间进行研究。

Superconducting cyclotrons are becoming the mainstay of modern proton-based radiotherapy, with several companies now offering treatment solutions based on the use of 230-250 MeV-output cyclotrons which are suitable for deep-seated tumours in adult treatments. However, delivery of low-energy protons from 30 to 70 MeV using these large cyclotrons is technically problematic and a lower-energy design - suitable for example for eye therapy and other shallow treatments - is needed; Clatterbridge Cancer Centre developed the world's first hospital proton therapy service of any kind, but is now looking to replace its machine with a more modern, sophisticated variant with the assistance of Antaya Science and Technology; Antaya is an accelerator development company with world-leading experience in designing medical cyclotrons.This PhD project will entail using Antaya's experience and technology platform, and apply it to Clatterbridge's clinical requirements to develop a cyclotron design and associated beam delivery system, intended to be a replacement for the present treatment system at Clatterbridge. The successful candidate will split their studies between the Cockcroft Institute (Cheshire, UK, working on beam delivery design), the Clatterbridge Cancer Centre (Wirral, UK, performing measurements and developing a clinical specification), and the development facility of Antaya Science and Technology (New Hampshire, USA, working on cyclotron design).