Comprehensive MMC/VICC Cancer Research Partnership

众所周知，少数群体患癌症的比例过高，死亡率和发病率都存在差异。其他公认的问题是，从事癌症研究的少数群体科学家和医生很少，而参加临床试验的少数群体人数过多。Meharry医学院（MMC）有着杰出的历史，培训了目前活跃在美国的大部分非洲裔美国医生。虽然MMC长期以来一直活跃在癌症研究中，但这些活动的前景尚未实现。范德比尔特-英格拉姆癌症中心（VICC）是一个研究密集型的国家癌症研究所指定的癌症中心，具有非常强大的基础，转化，临床，预防和人口为基础的研究计划。MMC和VICC位于纳什维尔内，相距约2英里。两个机构之间的教师互动有着悠久的历史，最近成立的Meharry-Vanderbilt联盟为在CCSG补充的支持下快速发展MSI/CC合作伙伴关系提供了基础设施。U 54申请的总体目标是加强和扩大MMC和VICC之间现有的癌症研究合作伙伴关系，以实现三个目标：（1）扩大MMC和VICC之间现有的癌症研究合作伙伴关系，以实现三个目标：（1）提高和稳定MMC的竞争癌症研究能力;（2）在MMC和VICC之间建立稳定的长期合作关系，开展活动，重点关注中南部少数民族人口中不成比例的发病率、死亡率和发病率。我们为实现这些目标而设计的计划由每个机构的管理以及规划和评估的适度核心指导。该项目的研究活动包含在一个发展核心中，该核心由基础科学、癌症预防、成果和推广以及临床研究组成。我们建议资助六个试点项目和四个共享资源。两名基础科学家，一名医学肿瘤学家，一名外科肿瘤学家和两名流行病学家，将被招募加入MMC教师与联合任命在范德比尔特的赞助下，这笔赠款。我们建议通过正式的培训计划和少数医学肿瘤学家，少数研究护士和数据管理员，少数博士的培训MMC教师的职业发展。候选人和MMC医学生在基础和临床癌症研究。

It is well known that minority groups suffer disproportionately from cancers with disparities existing in both the mortality and incidence rates. Other well-recognized problems are the paucity of minority scientists and physicians working in cancer research and the disproportionate number of minorities being entered into clinical trials. Meharry Medical College (MMC) has a distinguished history of training a large percentage of the African American physicians currently active in the United States. While MMC has long been active in cancer research, the promise of these activities has not yet reached fruition. Vanderbilt- Ingram Cancer Center (VICC) is a research intensive NCI-designated cancer center with very strong basic, translational, clinical, prevention and population-based research programs. MMC and VICC are located approximately two miles apart within Nashville. There has been a long history of faculty interactions between the two institutions, and the more recent establishment of the Meharry-Vanderbilt Alliance has provided the infrastructure for the rapid development of a MSI/CC partnership with support from the CCSG supplement. The overall objectives of this U54 application are to strengthen and expand the existing partnership for cancer research between MMC and the VICC to achieve three ends: (1) to expand the existing partnership for cancer research between MMC and the VICC to achieve three ends: (1) to increase and stabilize the competitive cancer research capability of MMC; (2) to create, stable, long term collaborative relationships between MMC and VICC in conducting activities focused on the disproportionate incidence, mortality and morbidity in minority populations in the mid-south. The programs we have designed to achieve these ends are guided by modest cores for administration at each institution and for planning and evaluation. Research activities for the project are contained in a development core that consists of components in basic science, cancer prevention, outcomes and outreach, and clinical investigations. We propose funding of six pilot projects and four shared resources. Two basic scientists, one medical oncologist, one surgical oncologists and two epidemiologists, will be recruited to join the MMC faculty with joint appointments at Vanderbilt under the auspices of this grant. We propose career development of MMC faculty through formal training programs and training of a minority medical oncologist, minority research nurses and data managers, minority Ph.D. candidates, and MMC medical students in basic and clinical cancer research.