SUBSTANCE USE: FAMILY, FRIEND, AND COMMUNITY FACTORS

描述：(申请人摘要) 这次申请K02奖项的具体目的是为了推进 申请者的量化技能，这反过来将使她能够在 她已经具备了定性和定量的技能，而且在很大程度上 她对药物滥用领域做出了质的贡献。大部分 她在药物滥用领域的工作本质上是定性的，或者是 仅限于不太先进的量化方法。最终，这位候选人 预计拥有丰富的高级质量和 量化技能将使她继续为 菲尔德。在研究计划中，申请者建议在她正在进行的基础上 母女代际药物滥用研究。 虽然关于药物滥用的家庭、朋友和社区因素的研究 存在，关于风险之间的复杂关系仍然存在许多问题 以及这三个水平上的保护性因素。在这项拟议的研究中， 候选人的目标是：(1)确定药物使用、滥用的家庭模式 和依赖可卡因的年轻人(18-25岁)、他们的父母 还有他们的兄弟姐妹。这包括特定家庭成员、家庭成员的作用 特效药的聚集性、家族用药模式及其发展 家族性物质使用；(2)探讨可卡因与 依赖和共病的精神病理，特别是抑郁，焦虑， 反社会性人格障碍和创伤后应激综合征； 考察特定的社区因素在物质发展中的作用 使用、滥用和依赖。这些因素涉及当地的毒品市场力量， 例如可卡因和其他药物的可获得性、价格和纯度； 关于物质使用的社区规范，以及其他相关社区 特征；以及(4)调查风险和保护的动态 个人、家庭和社区层面的因素。中国的发展和 应用程序的培训部分包括高级课程作业 统计技术。这项进一步的培训将使申请人能够 继续在她现有的专业知识基础上继续取得 通过在很大程度上增加量化方法对该领域的贡献 质的工作。从教学和行政部门请求的释放时间 责任将允许应聘者提升她的研究事业。

DESCRIPTION: (Applicant's Abstract) The specific aim of this application for a K02 award is to advance the applicant's quantitative skills, which in turn will allow her to build on the qualitative and quantitative skills she already has as well as on the largely qualitative contributions she has made to the substance abuse field. Much of her work in the substance abuse field has been qualitative in nature or been limited to less advanced quantitative approaches. Ultimately, the candidate anticipates that an extensive knowledge of advanced qualitative and quantitative skills will allow her to continue to make contributions to the field. In the research plan, the applicant proposes to build on her ongoing research on intergenerational substance abuse among mothers and daughters. Although research on familial, friend, and community factors on substance abuse exists, many questions remain regarding the complex relationship between risk and protective factors at all three of these levels. In the proposed research, the candidate aims: (1) to determine familial patterns of substance use, abuse and dependence among cocaine-dependent young adults (ages 18-25), their parents and their siblings. This includes the role of specific family members, familial aggregation, familial use patterns of specific drugs, and the development of familial substance use; (2) to explore the association between cocaine dependence and comorbid psychopathology, particularly depression, anxiety, antisocial personality disorder, and post-traumatic stress syndrome; (3) to examine the role of specific community factors in the development of substance use, abuse, and dependence. These factors involve local drug market forces, such as the availability, price and purity of cocaine and other drugs; community norms regarding substance use, and other relevant community characteristics; and (4) to investigate the dynamics of risk and protective factors at the individual, familial, and community levels. The development and training component of the application includes course work in advanced statistical techniques. This further training will allow the applicant to continue to build on her existing expertise and to continue to make contributions to the field by adding quantitative approaches to her largely qualitative work. The requested release time from teaching and administrative responsibilities will allow the candidate to enhance her research career.