Microbiological Air Contamination from Machining Fluids

描述(申请人提供)：接触机加工液的工人 气雾剂可能会增加患上各种呼吸系统疾病和 皮肤病。美国约有120万工人 职业接触金属加工液(MWF)。最近的研究表明 表明从MWFS中散布的微生物会导致严重的呼吸道疾病 工人中的疾病。然而，在网上提供的信息不足 金属加工场所空气微生物的组成和浓度。 此外，MWFS中的雾气和微生物的分散性很差 明白了。我们计划研究雾气和微生物的气雾化 MWFS使用我们的新技术进行气雾化和测量 生物气雾剂。这项为期两年的研究的一个关键工具是我们新开发的 生物采样器设计用于生物气溶胶的长期采样。实验将会 首先在实验室中通过模拟在受控条件下进行 几种不同的加工条件。实验室规模的雾气发生器， 由Milacron Inc.的科学家开发，将被采用并为此进行修改 研究，并将与代表不同粘度和表面的MWF一起使用 紧张。雾气的气雾化将首先用清洁的液体进行测试， 用接种了已知浓度的测试微生物的液体，以及 最后，使用从现场试验场收集的二手液体。最后一个阶段是 实地调查。现场数据与实验室数据的比较将使 美国将解释雾和微生物在MWF环境中的扩散 并评估工人潜在的微生物暴露。两者都是必需的 制定工程控制策略。实地考察也将对我们有所帮助 创建一个关于空气中微生物浓度的初始数据库 MWF环境。这一项目的发现有望对 制定或修改减少与健康相关的危害的标准 对MWF的暴露。

DESCRIPTION (provided by applicant): Workers exposed to machining fluid aerosols may have an increased risk in developing a variety of respiratory and skin diseases. About 1.2 million workers in the United States are occupationally exposed to metalworking fluids (MWFs). Recent studies have suggested that microorganisms dispersed from MWFs can cause severe respiratory diseases in workers. However, insufficient information is available on the composition and concentration of airborne microorganisms at metalworking sites. Furthermore, the dispersion of mist and microorganisms from MWFs is poorly understood. We plan to study the aerosolization of mist and microorganisms from MWFs using our new techniques for the aerosolization and measurement of bioaerosols. A key instrument in this 2-year study is our newly developed BioSampler designed for long-term sampling of bioaerosols. Experiments will first be performed in the laboratory under controlled conditions by simulating several different machining conditions. A laboratory-scale mist generator, developed by scientists at Milacron Inc., will be adopted and modified for this study, and will be used with MWFs representing different viscosity and surface tension. The aerosolization of mist will be tested first with clean fluids, with fluids inoculated with known concentrations of test microorganisms, and finally with used fluids collected from field test sites. The last phase is a field study. Comparison of the field data with the laboratory data will allow us to interpret the dispersion of mist and microorganisms in MWF environments and to assess the potential microbial exposure of workers. Both are needed developing engineering control strategies. The field study will also help us create an initial database on the concentrations of airborne microorganisms in MWF environments. The findings of this project are expected to contribute toward setting or modifying standards for reducing the health hazards related to MWF exposure.