Green Housing Study: Measures of Housing Factors and Pediatric Respiratory Health

绿色住房研究：住房因素和儿童呼吸健康的测量

• 批准号: 8413246
• 负责人: Tiina Reponen
• 金额: $ 18.75万
• 依托单位: UNIVERSITY OF CINCINNATI
• 依托单位国家: 美国
• 财政年份: 2012
• 资助国家: 美国
• 起止时间: 2012-07-01 至 2014-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8413246
• 关键词: Green; Housing; Study; Measures; Factors

DESCRIPTION (provided by applicant): It is assumed, as conventional wisdom, that the green building design features are effective in reducing allergens and toxic substances within the home. Scientifically credible evidence is needed as to the extent to which green-built, low-income housing actually reduces exposures to these hazards when compared to standard-built, low-income housing. Green housing utilizes various strategies to reduce environmental contaminants. It is hypothesized that these strategies will lead to 1) lower levels of environmental contaminants in green housing compared to those of control housing, and 2) lower levels of related biomarkers of exposure in the residents of green vs. control housing. The reduction of irritants and allergens in green vs. control housing may result in improved asthma morbidity among residents of green housing. Specifically, we hypothesize that children with asthma (ages 7-12 years) who reside in green housing will have lower asthma morbidity, adjusting for environmental tobacco smoke (ETS) exposure. This hypothesis will be tested through two specific aims: (1) To conduct an exposure assessment of chemical and biological contaminants, pesticides, volatile organic compounds (VOCs), fungi, indoor allergens (in terms of variety and concentration) in green and comparison housing, and (2) To examine the association between residing in green vs. comparison housing and asthma morbidity (e.g., symptoms, emergency department visits, use of medications, lost school/work days) of children with doctor-diagnosed asthma (ages 7-12 years). Environmental and clinical assessments will be conducted in 32 green renovated apartments at baseline (immediately after renovation) and at 6 and 12 months after renovation. Parallel assessments will be conducted in 32 non-renovated apartments. The study in Cincinnati is part of a nationwide Green Housing study conducted in close partnership with the Centers for Disease Control and Prevention (CDC) and U.S. Department of Housing and Urban Development (HUD). Cincinnati is one of the first metropolitan areas being assessed in this multicenter study; Boston, Massachusetts is being simultaneously assessed by the Harvard School of Public Health. The nationwide multi-site design will provide contextual information to understand which green building rehabilitation practices are associated with health not only regionally, but nationally. This elucidation then could inform policy about which green components should be implemented without regard to locality, and which components should be modified under certain circumstances (e.g., region or housing type). PUBLIC HEALTH RELEVANCE: The study is expected to provide insight into how specific green building practices (e.g., use of low chemical-emitting paints and carpets) influence levels of substances in the home (such as volatile organic compounds and pesticides) and how asthmatic children's health is affected by these changes. The results will inform policy makers about the benefits of specific green components.

描述（由申请人提供）：作为传统智慧，假设绿色建筑设计特征在减少家中的过敏原和有毒物质方面是有效的。需要有科学上可信的证据来证明，与标准建造的低收入住房相比，绿色建造的低收入住房实际上在多大程度上减少了对这些危害的暴露。绿色住宅利用各种策略来减少环境污染物。假设这些策略将导致1）与对照圈养动物相比，绿色圈养动物中的环境污染物水平较低，以及2）与对照圈养动物相比，绿色圈养动物中暴露的相关生物标志物水平较低。与对照组相比，绿色住房中刺激物和过敏原的减少可能导致绿色住房居民哮喘发病率的改善。具体来说，我们假设，居住在绿色住房的哮喘儿童（7-12岁）将有较低的哮喘发病率，调整环境烟草烟雾（ETS）暴露。将通过两个具体目标对这一假设进行检验：（1）对绿色和对照住房中的化学和生物污染物、杀虫剂、挥发性有机化合物（VOC）、真菌、室内过敏原（在种类和浓度方面）进行暴露评估，以及（2）检查居住在绿色和对照住房中与哮喘发病率之间的关联（例如，症状、急诊室就诊、药物使用、失学/工作日）。将在32套绿色翻新公寓的基线（翻新后立即）以及翻新后6个月和12个月进行环境和临床评估。将对32套未经翻修的公寓进行平行评估。辛辛那提的这项研究是与疾病控制和预防中心（CDC）和美国住房和城市发展部（HUD）密切合作进行的全国性绿色住房研究的一部分。辛辛那提是这项多中心研究中最早评估的大都市地区之一;马萨诸塞州的波士顿也同时接受了哈佛公共卫生学院的评估。全国范围内的多站点设计将提供上下文信息，以了解哪些绿色建筑修复实践不仅与区域健康有关，而且与全国健康有关。然后，这种说明可以告知政策，哪些绿色组件应该在不考虑地点的情况下实现，以及哪些组件应该在某些情况下修改（例如，区域或住房类型）。 公共卫生相关性：该研究预计将深入了解具体的绿色建筑实践（例如，使用低化学排放的油漆和地毯）会影响家中物质（如挥发性有机化合物和杀虫剂）的水平，以及这些变化如何影响哮喘儿童的健康。研究结果将使决策者了解具体绿色组成部分的好处。