Design of a Compact Cyclotron for Proton Therapy

超导回旋加速器正在成为现代质子放射治疗的支柱，有几家公司现在提供基于使用230-250 mev输出的回旋加速器的治疗方案，适用于成人治疗的深部肿瘤。然而，使用这些大型回旋加速器输送30至70兆电子伏的低能质子在技术上是有问题的，需要一种低能量的设计——适合于例如眼部治疗和其他浅层治疗；克拉特布里奇癌症中心开发了世界上第一个医院质子治疗服务，但现在正寻求在安塔亚科技的帮助下，用更现代、更复杂的变体来取代它的机器；Antaya是一家加速器开发公司，在设计医用回旋加速器方面拥有世界领先的经验。该博士项目将利用Antaya的经验和技术平台，并将其应用于Clatterbridge的临床需求，以开发回旋加速器设计和相关的光束输送系统，旨在取代Clatterbridge目前的治疗系统。成功的候选人将在科克罗夫特研究所（英国柴郡，从事光束输送设计）、克拉特布里奇癌症中心（英国威勒尔，进行测量和制定临床规范）和Antaya科技公司的开发设施（美国新罕布什尔州，从事回旋加速器设计）之间进行研究。

Superconducting cyclotrons are becoming the mainstay of modern proton-based radiotherapy, with several companies now offering treatment solutions based on the use of 230-250 MeV-output cyclotrons which are suitable for deep-seated tumours in adult treatments. However, delivery of low-energy protons from 30 to 70 MeV using these large cyclotrons is technically problematic and a lower-energy design - suitable for example for eye therapy and other shallow treatments - is needed; Clatterbridge Cancer Centre developed the world's first hospital proton therapy service of any kind, but is now looking to replace its machine with a more modern, sophisticated variant with the assistance of Antaya Science and Technology; Antaya is an accelerator development company with world-leading experience in designing medical cyclotrons.This PhD project will entail using Antaya's experience and technology platform, and apply it to Clatterbridge's clinical requirements to develop a cyclotron design and associated beam delivery system, intended to be a replacement for the present treatment system at Clatterbridge. The successful candidate will split their studies between the Cockcroft Institute (Cheshire, UK, working on beam delivery design), the Clatterbridge Cancer Centre (Wirral, UK, performing measurements and developing a clinical specification), and the development facility of Antaya Science and Technology (New Hampshire, USA, working on cyclotron design).