Effects Of Dental Treatment During Pregnancy On Childhoo

目的：评价妊娠期牙科治疗的潜在风险及其对儿童发育的影响。程序和技术：我们与雅芳妊娠和儿童纵向研究（ALSPAC）合作。他们收集了1.4万名妇女及其子女的怀孕数据，我们正在分析这些数据，以研究怀孕期间的牙科治疗（接触感染和汞蒸气）、产前和产后食用鱼类与儿童发育之间的关系。成果：我们研究了问卷测量与脐带汞含量之间的关系。报告的鱼类消费量与脐带汞水平之间存在很强的相关性，这表明脐带测量可能是胎儿接触甲基汞的有用测量。与朱莉·丹尼尔斯博士合作，她将领导其中的一些分析，我们正在分析怀孕期间的牙科治疗，产前和产后吃鱼之间的关系在两个儿童发展量表上，丹佛发展量表和麦克阿瑟交流量表。初步结果表明，通过这两个量表评估，牙科汞接触对18个月大的儿童发育没有不利影响。此外，食用鱼类似乎具有高度的保护作用。

Aims: To evaluate the potential risks of dental treatment during pregnancy and effects on childhood development. Procedures and techniques: We are collaborating with the Avon Longitudinal Study of Pregnancy and Children (ALSPAC). They have collected data on the pregnancies of 14,000 women and their children and we are analyzing the data to look at the relationship between dental treatment during pregnancy (exposures to infection and to mercury vapor), prenatal and postnatal fish consumption and childhood development. Accomplishments: We have looked at the relationship between the questionnaire measures and umbilical cord mercury levels. There is a strong correlation between reported fish consumption and umbilical cord mercury levels, which suggests that the umbilical cord measure may be a useful measure of fetal exposure to methyl mercury. Working with Dr. Julie Daniels, who will be taking the lead on some of these analyses, we are in the process of analyzing the relationship between dental treatment during pregnancy, prenatal and postnatal fish consumption on two childhood development scales, the Denver developmental Scale and the Macarthur communication scale. Preliminary results suggest that dental mercury exposures did not have an adverse effect on child development at 18 months as assessed by these two scales. In addition, fish consumption appeared to be highly protective.