ASSESSMENT MODE AND VALIDITY OF SELF-REPORTS IN CHILDREN

描述(改编自调查人员摘要)：自我报告是主要的 行为数据的来源。这个课题组已经进行了先前的研究 显示许多患者过度报告治疗依从性，即自我报告 无论是通过面对面的采访还是通过临床试验提供的信息都是不可靠的 日记卡片和父母是更不可靠的忠诚度来源 比孩子们更了解信息。计算机辅助面试已经多次 比面对面的采访或纸和笔透露了更多的信息 关于高危性行为和吸毒行为的问卷，但没有 在此之前被应用于慢性儿科疾病的依从性评估。 这项拟议的研究的主要目标是检查 吸入性疾病患者自我报告效度的数据收集模式 与客观标准相比，抗炎药物的依从性 是通过电子监控获得的。我们假设他的自我报告 服药依从性与客观指标的一致性最低 在最高评估个性化的条件下(即面对面 访谈)和最低评估条件下的最高一致性 个性化(即电话、计算机辅助面试)。此外，儿童 预计会比他们的父母更准确的记者，但那个父母 儿童差异会随着儿童年龄的增加而减少。儿童哮喘 患者(N=120)将参加为期6个月的哮喘教育研究 将被随机分为：1)以临床为基础的面试者进行问卷调查， 2)基于诊所的计算机辅助数据收集，或3)基于家庭的数据收集 计算机辅助电话采访。父报告和子报告将是 分开收集。客观的、电子记录的遵守数据将是 与自我报告相比。我们还将研究面试模式如何影响 对包括哮喘症状和质量在内的其他结果测量的自我报告 生活。这项研究的结果，以及我们合作的结果 互动研究项目资助(IRPG)机构(约翰霍普金斯大学)，将 演示数据收集方法如何影响自我报告并帮助 确定临床研究环境中的最佳自我报告策略。结果 从这次调查中预计将产生直接和直接的影响 用于哮喘和其他慢性疾病的临床研究。

DESCRIPTION (adapted from investigator's abstract): Self-reports are a primary source of behavioral data. This research group has conducted previous research showing that many patients over-report treatment adherence, that self-reports are unreliable whether provided by face-to-face interview or by clinical trial diary card and that parents are even less reliable sources of adherence information than children. Computer-assisted interviewing has repeatedly revealed more information than face-to-face interviewing or paper-and-pencil questionnaires about high risk sexual and drug-use behaviors, but has not before been applied to adherence assessment in chronic pediatric conditions. The primary objective of this proposed study is to examine the influence of mode of data collection on the validity of self-reports of inhaled anti-inflammatory medication adherence, as compared with an objective criterion obtained via electronic monitoring. We hypothesize that self-reports of medication adherence will have the lowest concordance with objective measures under conditions of highest assessment personalization (i.e. face-to-face interview) and highest concordance under conditions of lowest assessment personalization (i.e. telephone computer-assisted interview). Further, children are expected to be more accurate reporters than their parents, but that parent child-discrepancy will decrease with increasing child age. Pediatric asthma patients (N=120) will be enrolled in a six-month asthma education study and will be randomized to: 1) clinic-based interviewer administered questionnaire, 2) clinic-based computer-assisted data collection, or 3) home-based computer-assisted telephone interview. Parent reports and child reports will be collected separately. Objective, electronically recorded adherence data will be compared with self-reports. We will also examine how interview mode influences self-reports of other outcome measures including asthma symptoms and quality of life. Results of this study, together with those from our collaborative Interactive Research Project Grant (IRPG) institution (Johns Hopkins), will demonstrate how data collection methods influence self-report and serve to identify optimal self-report strategies in clinical research settings. Results from this investigation are expected to have immediate and direct implication for clinical research in asthma and with other chronic conditions.