INIA: Informatics Core

描述(由申请人提供)： 酒精中毒综合神经科学倡议的信息学核心 (INIA)提供中央信息和计算资源 不同的INIA研究项目和核心。这个INIA信息学核心将， 第一，提供协同信息管理、信息 对这些INIA项目至关重要的技术和数据库 获取和管理他们的数据。信息学核心将开发一些 协作信息系统应有助于分解地理位置 科学协作的障碍；这一核心将使评价和 直接应用这些信息技术支持的协作工具 供MA研究人员使用。为了进行探索性研究，几个电子设备 将开发实验室笔记本。此外，可通过网络访问的实验室 还将为更大规模的数据发现建立信息系统 允许集中跟踪和共享非常不同类型的 同一小鼠品系的表型数据来自不同的研究实验室和 机构。其次，这个核心将提供一些计算分析和 数据挖掘工具，使INIA的研究人员能够筛选他们的 有趣的模式的数据，特别是可能表明 可以通过进一步的实验来检验的假设。此外，核心 将有助于启动和促进试验性INIA之间的合作 研究人员和其他计算研究人员可能不会直接 由该项目资助。第三，这个核心需要使完成的INIA 通过数据库支持的Web向整个社区免费提供信息 并促进其数据与来自其他项目的数据的互通性。 对于社区数据库可以接受的数据子集，信息学 CORE需要将这些数据打包并转发给他们。这个核心将会工作 与其他信息学研究人员和开发人员一起研究通用数据模式， 领域本体、数据格式和其他促进互操作性的方式 跨不同的数据和数据库。

DESCRIPTION (provided by applicant): The Informatics Core of the Integrative Neurosciences Initiative on Alcoholism (INIA) provides central informational and computational resources for the different INIA research projects and cores. This INIA informatics core will, first, provide the collaborative information management, information technologies, and databases that are critical for these INIA projects to acquire and manage their data. The informatics core will develop a number of collaborative information systems that should help break down the geographic barriers to scientific collaboration; this core will enable the evaluation and direct application of these information-technology-backed collaborative tools for use by MA researchers. For exploratory research, several electronic laboratory notebooks will be developed. In addition, web-accessible lab information systems will also be built for larger-scale data discovery projects that allow central tracking and sharing of very different kinds of phenotype data about the same mouse strain from different research labs and institutions. Secondly, this core will provide some computational analysis and data mining tools that should enable INIA researchers to sift through their data for interesting patterns, especially patterns that might suggest hypotheses that can be tested by further experiments. In addition, the core will help initiate and foster collaborations between experimental INIA researchers and other computational researchers that might not be directly funded by this project. Thirdly, this core needs to make the finished INIA information freely available to the entire community via database-backed web sites and promote interperability of its data with data from other projects. For the subset of data that a community database can accept, the informatics core will need to package and forward that data to them. This core will work with other informatics researchers and developers on common data schemas, domain ontologies, data formats, and other ways to promote interperability across different data and databases.