Scholars in Women's Health Research across the Lifespan

描述（由申请人提供）：俄勒冈BIRCWH发展计划的目标是为初级教师创造一个激励和培养的环境，使其发展成为妇女健康领域领先的内科科学家。该计划认识到，研究可以在女性生命的某个阶段改变疾病的进程，并影响终身发展和衰老的其余部分。该计划将基础和临床初级教员科学家与来自不同背景的具有妇女健康问题专业知识的既定导师配对，以提高学者的研究能力。职业道路和背景的混合将是在整个生命周期中增加合作和促进妇女健康研究的组成部分。在俄勒冈健康与科学大学（OHSU）广泛的智力和研究资源是可用的，并致力于发展BIRCWH学者。整合是跨部门的，将加强妇女健康中心、心脏研究中心、灵长类动物研究中心和癌症研究所的科学家之间在妇女健康方面的现有合作。在分子生物学、细胞培养、DNA分析、成像、统计学、辅助生殖技术、内分泌测定、实验动物、转基因和分子遗传学核心等方面，已经建立了先进的研究核心实验室，并将向BIRCWH学者开放。为临床科学家设计临床研究和统计评估的高级培训将通过非常成功的SOM人类调查计划进行协调。BIRCWH计划的导师是获得资助的科学家，他们将在妇女健康的整个生命周期领域为学者提供多样化和深入的指导。最初的BIRCWH项目将重点关注六个主要领域：胎儿环境在心血管功能编程中的终身性别差异；生殖和健康，包括排卵、正常/异常分娩、激素对盆底功能的影响和更年期；神经生物学和性别差异；妇女滥用药物；妇女癌症；女性衰老和生命终结的研究。

DESCRIPTION (provided by applicant): The goal of the Oregon BIRCWH Development Program is to create a stimulating and nurturing environment for junior faculty to develop into leading Physician Scientists in Women's Health. The program recognizes that research can modify the course of disease at one point in a woman's lifespan and affect the rest of lifelong development and aging. The program pairs basic and clinical junior faculty scientists with established mentors from different backgrounds who have expertise in Women's Health Issues in order to enhance the scholar's research capabilities. The mix of career paths and backgrounds will be integral to increasing collaboration and invigorating research in Women's Health across the lifespan. The extensive intellectual and research resources at the Oregon Health & Science University (OHSU) are available and committed to developing BIRCWH scholars. Integration is interdepartmental and will enhance existing collaborations in Women's Health between scientists in the Center for Women's Health, the Heart Research Center, the Primate Research Center and the Cancer Institute. Sophisticated research core laboratories specializing in Molecular Biology, Cell Culture, DNA analysis, Imaging, Statistics, Assisted Reproductive Techniques, Endocrine Assays, Laboratory Animal, Transgenic and Molecular Genetics Cores, among others, have already been established and will be available to the BIRCWH Scholars. Advanced training in designing clinical studies and statistical evaluation for clinician scientists will be coordinated through the highly successful SOM Human Investigations Program. The mentors of this BIRCWH Program are funded scientists who will provide diverse and in-depth mentorship for scholars in areas of women's health that extend across the lifespan. Six major areas of focus will constitute the initial BIRCWH program: fetal environment in programming lifelong gender differences in cardiovascular function; reproduction and health which includes ovulation, normal/abnormal parturition, hormonal effect upon pelvic floor function and menopause; neurobiology and gender differences; substance abuse in women; cancers of women; aging and end of life research in women.