Graduate Training in Biochemistry and Molecular Biology

描述(申请人提供)：现代生物学正进入一个新时代。这个 多种生物的基因组已经完全测序，数量繁多 基因组规模的项目正在进行中。这些项目正在产生大量的 潜在基因产物、RNA和蛋白质表达谱数据库， 与基因类型相关的表型和结构信息。此信息 为前所未有的生物学洞察力提供了基础，这具有巨大的 可能对生物医学研究产生影响。然而，至关重要的是， 对新科学家进行培训，以利用这些生物信息。 21世纪优秀科学家的三个基本特征 世纪：1)基本了解复杂的生物化学、分子和生物化学 正常情况下共同控制生理动态平衡的细胞过程 以及疾病缠身的州。2)理解和利用来自 开发新的生物学洞察力的多学科。3)能够 有效地沟通双方的研究目标和科学发现 口头和书面形式，向其他科学家、教育工作者、立法者和 平民百姓。为了培训具有这些必要技能的个人，有八个 几年前，我们制定了一个跨部门的博士培训计划， 强调以跨学科的方法进行科学研究，重点是 生物化学、分子和细胞生物学领域。这笔赠款是第一笔 续签部分资助学生的培训补助金 程序。这一群体所代表的研究专业知识的深度和广度 他们对研究生教育的承诺是根本 为拟议的跨学科培训奠定基础。

DESCRIPTION (provided by applicant): Modern biology is entering a new era. The genomes of multiple organisms have been completely sequenced and numerous genomic scale projects are ongoing. These projects are generating vast databases of potential gene products, RNA and protein expression profiles, phenotypes linked to genotypes, and structural information. This information provides the foundation for unprecedented biological insight, which has great potential to impact on biomedical research. However, it will be critical that new scientists be trained to take advantage of this biological information. Three essential attributes will characterize excellent scientists of the 21st century: 1) A fundamental knowledge of the complex biochemical, molecular and cellular processes that together control physiological homeostasis under normal and diseased states. 2) The ability to understand and utilize information from multiple disciplines to develop new biological insights. 3) The ability to effectively communicate research objectives and scientific findings in both oral and written form, to other scientists, to educators, to legislators, and lay citizens. In order to train individuals with these necessary skills, eight years ago we developed an interdepartmental Ph.D. training program that emphasizes an interdisciplinary approach to scientific research focused on the areas of biochemistry, molecular and cellular biology. This grant is the first renewal of the training grant that partially supports the students within the program. The depth and breadth of research expertise represented by this group of researchers, and their commitment to graduate education is the underlying foundation for the proposed interdisciplinary training.