Mechanically Chiral Rotaxanes in Catalysis, Sensing and Materials

在这个项目中，Arnau将研究互锁手性催化剂的对映选择性，其中机械键提供了唯一的立体单元，以证明这些系统的合成潜力。为此，他将合成一系列带有催化官能团的手性轮烷和索烃，并研究它们在熟知的催化反应中的行为。这些系统的长期应用是在医药和材料科学的手性分子的合成。

In this project Arnau will study the enantioselectivity of interlocked chiral catalysts in which the mechanical bond provides the sole stereogenic unit to demonstrate the synthetic potential of these systems. To do this he will synthesise a series of chiral rotaxanes and catenanes bearing catalytic functional groups and study their behaviour in well understood catalytic reactions. The long term applications of these systems is in the synthesis of chiral molecules for medical and materials science.