Upper Body Strength Training in COPD

描述（由申请人提供）：中度至重度慢性 阻塞性肺疾病（COPD）会出现严重的呼吸困难症状 当他们使用他们的手臂和肩膀。为了控制呼吸困难， 使用他们的上肢，并最终经历了显着的损失 上肢（UB）力量和功能表现下降，反映在 减少每天进行的活动。目的 这项研究的目的是检查UB力量训练的效果， 自我效能干预以提高依从性。这是一项实验性研究 将受试者随机分配到一个实验组和两个对照组： (a)UB力量训练与自我效能干预（实验），（B）UB 力量训练与健康教育（对照1）和（c）扶手椅健身 健康教育锻炼（对照2）。干预期为四个月 在为期12个月的随访期间，计划进行三次强化治疗 期每名受试者将接受总计16个月的研究。主 具体目标是比较短期（4个月）和长期（12个月） 结构化培训结束后）， 以下因变量的项：UB强度（一次重复 最大值），体力活动时呼吸困难（慢性呼吸道疾病 问卷调查）和功能性能（功能性能量表）。 次要目的是检查对吸气肌的影响 强度、运动相关自我效能和UB强度依从性 训练此外，将使用双能X线吸收测定法， 记录UB肌肉质量（无脂肪软组织）的变化。双加速度计 (arm和腰部）将用于验证锻炼坚持性的自我报告， 在12个月的随访中，样本将是120人， 在UB活动中发生呼吸困难的中度至重度COPD患者，40/ 组进行强度测试的研究人员将对分组不知情 派任这项研究是创新的，因为它检查了一个 综合上肢力量训练与举重（8个练习） 并将其与基于理论的自我效能干预相结合，以促进 坚持训练。这一点很重要，因为COPD患者会经历 恶化对依从性产生不利影响。该领域的以往研究 没有解决多次举重练习和长期 坚持。

DESCRIPTION (provided by applicant): People with moderate to severe chronic obstructive pulmonary disease (COPD) experience intense symptoms of dyspnea when they use their arms and shoulders. To control the dyspnea people avoid the use of their upper extremities and ultimately experience a significant loss of upper body (UB) strength and a decrease in functional performance, reflected by a decrease in the level of activities performed on a daily basis. The purpose of this research is to examine the effects of UB strength training with a self-efficacy intervention to enhance adherence. This is an experimental study with random assignment of subjects to one experimental and two control groups: (a) UB strength training with self-efficacy intervention (experimental), (b) UB strength training with health education (control 1) and (c) armchair fitness exercises with health education (control 2). The interventions are four months in duration with three booster sessions scheduled during a 12 month follow up period. Each subject will be studied for a total of 16 months. The primary specific aims are to compare the short (4 months) and long term (12 months after termination of structured training) effects of the above interventions in terms of the following dependent variables: UB strength (one-repetition maximum), dyspnea during physical activities (Chronic Respiratory Disease Questionnaire) and functional performance (Functional Performance Inventory). Secondary aims are to examine the effects in terms of inspiratory muscle strength, exercise-related self-efficacy, and adherence to UB strength training. Additionally dual energy x-ray absorptiometry will be used to document changes in UB muscle mass (fat free soft tissue). Dual accelerometers (arm and waist) will be used to verify self-report of exercise adherence at home during the 12 months follow-up. The sample will be 120 people with moderate to severe COPD who experience dyspnea with UB activities, 40 per group. Researchers performing strength tests will be blinded to group assignment. This research is innovative in that it examines the effects of a comprehensive upper body strength training with weight lifting (8 exercises) and combines it with a theory-based self-efficacy intervention to promote adherence to training. This is important because people with COPD experience exacerbations that adversely affect adherence. Previous research in this area does not address the effect of multiple weight lifting exercises and long-term adherence.