Nine mega-pixel digital mammography display workstation

描述（由申请人提供）：第一阶段：该申请致力于九百万像素数字乳房x线摄影工作站的开发和评估。长期目标是为放射科医生提供高分辨率，高亮度，最先进的审查工作站，以提高全视野数字乳房x光检查的临床接受度。实现这一目标的关键是实现图像质量优于当前CRT显示器的显示解决方案，并辅以集成的软件工具平台，以保证轻松的考试流程和高效的考试回顾。以下具体目标与此应用程序的第一阶段有关。(1)对现有的评审工作站进行改造，以实现一个原型平板工作站，并在此基础上进行AMLCD平板物理表征。(2)平台架构和软件规范的制定。(3)根据美国医学物理学家协会任务小组制定的标准指南完成平板表征18。(4)定义最佳亮度工作点及相关参数，实现灰度乳房x光片的最佳显示。(5)工作站高级功能规格的制定，包括双平板显示和平板在横向和纵向模式之间自动旋转。

DESCRIPTION (provided by applicant): Phase I: This application is devoted to the development and evaluation of a nine mega-pixel digital mammography workstation. The long-term objective is to provide radiologists with a high-resolution, high-luminance, state-of-the-art review workstation to improve the clinical acceptance of full-field digital mammography. Essential to the realization of this objective is the implementation of display solutions with image quality superior to that of current CRT displays, supported by an integrated platform of software tools to guarantee easy examination flow and efficient examination review. The following specific aims pertain to phase I of this application. (1) Modification of a current review workstation to implement a prototype flat-panel workstation from which to conduct the AMLCD flat-panel physics characterization. (2) Development of the platform architecture and software specifications. (3) Complete flat-panel characterization per the standard guidelines developed by the American Association of Physicists in Medicine task group 18. (4) Definition of the optimal luminance operating points and associated parameters, for optimal display of grayscale mammograms. (5) Development of the workstation advanced functionality specifications, including dual flat-panel display and automatic flat-panel rotation between landscape and portrait mode. Phase II: This application is devoted to the development and evaluation of a nine mega-pixel digital mammography workstation. The long-term objective is to provide radiologists with a high-resolution, high-luminance, state-of-the-art review workstation to improve the clinical acceptance of full-field digital mammography. Essential to the realization of this objective is the implementation of display solutions with image quality superior to that of current CRT displays, supported by an integrated platform of software tools to guarantee easy examination flow and efficient examination review. The following specific aims pertain to phase II of this application. (l) System design and integration. A significant part of the phase IT efforts will be devoted to engineering development work associated with the implementation of the review workstation architecture and software as defined in phase I. The main components of the RWS include the main computer, the graphics adapter cars, the software drivers for the graphics cards, and the main application software. (2) System optimization: psychophysics experiments to ascertain the impact of unique LCD characteristics on visual perception (including definition of the luminance operating range for optimal image display). (3) Pre-clinical evaluation and optimization with respect to the examination process flow. (4) Clinical validation: reader study for the mammography screening exam, conducted under two conditions: with CRT displays, and with fiat-panel displays. The measured outcomes will be area under the ROC curve, sensitivity, specificity, and interpretation time.