Core--Animal

动物核心的目的主要是协助研究人员进行动物手术、电生理学、行为测试和成像。该核心设施由执行项目1-4所述程序所需的人员和设备组成。动物中心将进行一般的动物准备，包括麻醉、气管切开、置管、体温监测和生理变量的调节。Core将协助研究者准备在个别项目中描述的脊髓损伤动物模型。此外，可以利用专业知识修改实验动物制剂，这可能是未来调查所需要的。工作人员还将协助对未来调查可能需要的动物制剂进行行为测试。工作人员还将协助对脊髓损伤后的大鼠进行行为测试，以及对特定白质束进行电生理评估。最后，该核心将为人类脊髓项目中脊髓挫伤的可视化提供MRI方面的专业知识。

The purpose of the Animal Core is primarily to assist investigators in animal surgery, electrophysiology, behavioral testing, and imaging. This Core facility consists of personnel and equipment needed to perform procedures described in Projects 1-4. The Animal Core will conduct general animal preparation, including anesthesia, tracheotomy, catheterizations, temperature monitoring and regulation of physiological variables. The Core will assist investigators in preparing the animal models of spinal cord injury described in the individual projects. In addition, expertise is available to modify experimental animal preparations that may be required for future investigations. Personnel will also assist in the behavioral testing of the animal preparations that may be required for future investigations. Personnel will also assist in the behavioral testing of the rats following spinal cord injury, as well as in electrophysiological assessment of specific white matter tracts. Finally, this Core will provide expertise in MRI for the visualization of spinal cord contusions within the human spinal cord project.