CORE--MEMBRANE BIOLOGY SUBCORE--PEPTIDE IODINATION

描述（摘自应用程序）：提供一个通用的设施， 激素、蛋白质、抗体和其他物质的放射性标记 125-I或131-I。具体来说，这意味着核心运行一个“热”， 实验室”与碘化罩和专用设备的蛋白质 洁净.所有程序均由技术人员或核心人员完成 导演我们发现这种方法有几个优点。的 核心产生的放射性物质是统一的， 在发布给调查人员之前进行质量标准化， 在同一个实验室进行的一系列实验之间的结果比较 实验室，在不同的实验室，或作为合作的一部分， study.实验室的效率和专业知识以及批量 常规标记化合物的生产也导致了大量的 节省（与商业购买的材料相比）、安全（与 校园内的多个小型碘化实验室）， 标记试剂的可用性， 商业上的，或者对于调查人员的日常使用来说太昂贵。

Description (taken from application): To provide a common facility for radioactive labeling of hormones, proteins, antibodies and other material with 125-I or 131-I. Specifically, this means that the Core runs a "hot lab" with an iodination hood and dedicated equipment for protein purification. All procedures are done by the technician or the Core Director. We have found several advantages to this method. The radioactive materials produced by the Core are uniform and routinely standardized for quality before being released to investigators, allowing comparison of results among a series of experiments done in the same laboratory, in different laboratories, or as part of a collaborative study. The efficiency and expertise of the laboratory as well as the bulk production of routinely labeled compounds has also resulted in substantial savings (versus commercially purchased materials), safety (compared with multiple small iodination laboratories across campus) and the ready availability of labeled reagents that are either not available commercially or are too costly for routine use by investigators.