Comprehensive Positioning Management System

描述（由申请人提供）： 我们计划开发和完善一个全面的位置管理系统（CPM系统）的前庭疾病的位置表现，在医疗和研究设施的广泛应用。利用可以以精确的方式对受试者进行自动定位的硬件（用于测试或治疗），再加上最先进的3D眼动记录和分析方法，该系统将显示数据，提供解释性指南，并协助进行复杂的操作。在第一阶段，我们将修改我们的原型系统，这些改进提供复杂的运动控制沿着3轴和眼球运动分析能力。 将开发交互式显示和控制的基本软件，并具有审查基本管理-指导系统数据的能力。我们还将通过在患有眩晕/不平衡问题的一小群受试者（n=20）中进行可行性研究来证明改进系统的价值。我们将通过确定CPM系统与使用最佳商用设备进行诊断和治疗相比所带来的附加值来验证性能。 在第2阶段，我们预计将根据第1阶段的发现进行工程修改。我们还将采用最先进的旋转和重力感受测试系统;以及基于知识的专家系统。 将在几个测试中心构建和安装生产模型，以便在更大的受试者人群中进行人体研究，以获得更明确的验证和用户验收测试。

DESCRIPTION (provided by applicant): We plan to develop and refine a comprehensive positional management system (CPM System) for positional manifestations of vestibule disorders for widespread application at medical and research facilities. Utilizing hardware that can carry out automated positioning of the subject in a precise manner (for testing or treatment), coupled with state-of-the-art 3-D eye movement recording and analysis methods, the system will display the data, provide interpretive guidelines and assist in carrying out complex maneuvers. During phase I we will modify our prototype system these improvements to provide sophisticated motion control along 3 axes and eye movement analysis capabilities. Basic software will be developed for interactive display and control with the ability to review data from the basic management-guidance system. We will also demonstrate the value of the improved system by performing feasibility studies in a small cohort of subjects with vertigo/imbalance problems (n=20). We will validate performance by determining the added value that the CPM System brings as compared to diagnoses and treatment using the best commercially available equipment. During phase 2, we anticipate that engineering modifications will be made based upon phase 1 findings. We will also incorporate state-of-the-art systems for rotational and graviception tests; and a knowledge-based expert system. Production models will be built and installed in several beta sites for conducting human studies in a larger subject population to obtain more definitive validation and user acceptance testing.