Multidisciplinary Rheumatology Training Program

描述（由申请人提供）： 本提案是国家研究服务奖机构研究培训补助金（T32）的修订申请，用于资助约翰霍普金斯医疗机构的多学科流变学培训计划。总体目标是支持培训和促进优秀学术流变学家的发展。该计划将招募，培训和加强初级流变学研究人员的发展，并为学员提供严格的研究方法和指导研究项目的指导。这些研究人员将通过他们卓越的研究，进一步加深我们对人类风湿性疾病的理解。我们展示了优秀的部门和机构资源提供给博士后在风湿病学，包括程序教师谁是特殊的导师在临床调查，免疫学，分子生物学和遗传学，细胞生物学，微生物学，流行病学和生物统计学的学科，并详细描述了培训计划，以实现总体目标。 我们的培训环境专注于提供富有成效的临床，基础和转化研究培训计划。将追求以下具体目标：[1]为风湿病学博士后研究员提供严格的研究方法培训，适用于临床和基础研究的开展; [2]利用卓越的临床中心提供明确的风湿病患者人群，使研究员项目能够在实践层面上对已建立的患者群体进行研究;[3]在临床研究中，将风湿病学博士后研究员纳入临床研究。[3]在全国知名教师的监督下，从事高素质的研究项目，解决临床上重要的问题; [4]为每个博士后研究员整合多层次的指导，以完成富有成效的研究，独立性和成功的学术生涯的发展;和[5]通过学员成就的基准评估本培训计划的成果，包括提交同行评审的出版物、收到外部研究资金和培训后的学术职位，同时结合学员、培训计划教师、以及内部和外部咨询委员会，以相应地修改该计划。 项目主任（罗森博士）、联合主任（威格利博士和盖尔伯博士）和另外20名研究人员担任受训人员的教员顾问。两个科学家咨询委员会，一个由机构教师组成（内部咨询委员会），另一个由约翰霍普金斯以外的教师组成（外部咨询委员会），将向主任提供咨询并监督进展。

DESCRIPTION (provided by applicant): This proposal is a revised application for a National Research Service Award Institutional Research Training Grant (T32) to fund a Multidisciplinary Rheumatology Training Program at The Johns Hopkins Medical Institutions. The overall goal is to support the training and foster the development of outstanding academic rheumatologists. The program will recruit, train and enhance the development of junior rheumatology investigators, and provide trainees with rigorous instruction in research methodology and mentored research projects. These investigators will further our understanding of human rheumatic diseases through their excellence in research. We demonstrate the outstanding divisional and institutional resources available to postdoctoral fellows in rheumatology, including program faculty who are exceptional mentors in the disciplines of clinical investigation, immunology, molecular biology and genetics, cell biology, microbiology, epidemiology and biostatistics, and describe in detail the training program to achieve the overall goal. Our training environment is focused on providing a productive clinical, basic and translational research training program. The following specific aims will be pursued: [1] Provide rigorous training in investigational methods to rheumatology postdoctoral fellows, applicable to the conduct of both clinical and basic research; [2] Utilize clinical centers of excellence to provide access to well-defined rheumatic disease patient populations, enabling fellow projects to be conducted, at a practical level, on established patient cohorts; [3] Engage postdoctoral fellows in high caliber research projects addressing clinically important questions under the supervision of nationally renowned faculty; [4] Integrate multi-layered mentorship for each postdoctoral fellow to accomplish productive research, independence, and development of a successful academic career; and [5] Assess the outcomes of this training program through benchmarks of trainee accomplishment, including submission of peer-reviewed publications, receipt of external research funding and post-training academic position, while incorporating feedback from trainees, training program faculty, and internal and external advisory committees to modify the program accordingly. The Program Director (Dr. Rosen), Co-Directors (Drs. Wigley and Gelber), and twenty additional investigators serve as faculty advisors to the trainees. Two advisory committees of scientists, one consisting of Institutional faculty (Internal Advisory Committee), the other of faculty outside Johns Hopkins (External Advisory Committee), will advise the Directors and monitor progress.